PRKG1 anticorps (N-Term)

N° du produit ABIN127130

Détail du produit anti-PRKG1 anticorps

Antigène: PRKG1 (Protein Kinase, CGMP-Dependent, Type I (PRKG1))

Épitope: N-Term

Reactivité: Humain, Souris, Rat, Boeuf (Vache)

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PRKG1 est non-conjugé

Application: Western Blotting (WB)

Specificité: The antibody recognizes 75 kDa and 85 kDa PKG, corresponding to the Molecular Mass of twho PKG isoforms.

Purification: Immunoaffinity Chromatography

Immunogène: Synthetic peptide near the N-terminus of Human PKG.

Information d'application

Indications d'application: Western Blot: 0.5-4 μg/mL. Immunoprecipitation: 4-8 μg/mL. Immunohistochemistry: 4-8 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 0.5 mg/mL

Buffer: PBS, 0.01 % Thimerosal, 30 % Glycerol, 0.5 % BSA

Agent conservateur: Thimerosal (Merthiolate)

Précaution d'utilisation: This product contains thimerosal (merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: -20 °C/-80 °C

Stockage commentaire: Store the antibody undiluted at -20 °C or for long term storage (in aliquots) at -70 °C.

Détails sur PRKG1

Antigène: PRKG1 (Protein Kinase, CGMP-Dependent, Type I (PRKG1))

Autre désignation: CGK1 (PRKG1 Produits)

Synonymes: anticorps prkg1, anticorps zgc:63955, anticorps Pkgi, anticorps cGk1, anticorps 1, anticorps PKG, anticorps PRKG1B, anticorps PRKGR1B, anticorps cGK, anticorps cGK 1, anticorps cGK1, anticorps cGKI, anticorps cGKI-BETA, anticorps cGKI-alpha, anticorps CGKI, anticorps cGKI-beta, anticorps AW125416, anticorps Gm19690, anticorps Prkg1b, anticorps Prkgr1b, anticorps Prkg1beta, anticorps protein kinase, cGMP-dependent, type Ia, anticorps protein kinase, cGMP-dependent, type I, anticorps protein kinase, cGMP-dependent, type 1, anticorps prkg1a, anticorps PRKG1, anticorps prkg1, anticorps Prkg1

Sujet: PKGs are cyclic GMP-dependent protein kinases (also designed cGKs) that are classified into two types, PKGI and PKGII. Studies have shown that cGKs and cyclic AMP-dependent kinases (cAKs) are highly homologous protein kinase families with similar substrate specificities. Phosphorylation of cellular proteins by both families of kinases leads to alterations in calcium mobilization, protein phosphatase activity, ion channel function, gene transcription, smooth muscle contractility and platelet aggregation. However, recent studies using mice deficient in PKGs have shown that cGMP kinases regulate very specifically distinct pathways which are separate from those used by cyclic AMP kinases.Synonyms: CKG1A, CKG1B, PGK, PKG, PRKG1, PRKGR1A, PRKGR1B, cGKI-alpha, cGMP-dependent protein kinase 1

ID gène: 5592

NCBI Accession: NP_001091982

UniProt: Q13976