Western Blotting (WB), Immunohistochemistry (Frozen Sections) (IHC (fro))
Specificité
The antibody detects 73 kDa SGLT-1 from Human samples and in a lesser extent Mouse and Rat. A ~50 kDa cleavage fragment can also be detected in Jurkat cell lysate.
Purification
Affinity Chromatography on Protein A.
Immunogène
Synthetic peptide surrounding amino acid 594 of human SGLT-1
Western Blot: 0.5-4 μg/mL. Jurkat cell lysate can be used as a Positive Control. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
anticorps D22S675, anticorps NAGT, anticorps SGLT1, anticorps zgc:66074, anticorps zgc:85782, anticorps SLC5A1, anticorps Sglt1, anticorps solute carrier family 5 member 1, anticorps solute carrier family 5 (sodium/glucose cotransporter), member 1, anticorps SLC5A1, anticorps slc5a1, anticorps Slc5a1
Sujet
Glucose transporters are integral membrane proteins that mediate the transport of glucose and structurally related substances across cellular membranes. Two families of glucose transporter have been identified: the facilitated diffusion glucose transporter family (GLUT family), also known as uniporters and the sodium dependent glucose transporter family (SGLT family) also known as cotransporters or symporters. The SGLT1 gene encodes a protein that is involved in the active transport of glucose and galactose into eukaryotic and some prokaryotic cells.Synonyms: High affinity sodium-glucose cotransporter, NAGT, Na(+)/glucose cotransporter 1, Sodium/glucose cotransporter 1, Solute carrier family 5 member 1