SLIT1 anticorps (AA 487-504)

N° du produit ABIN129640

Détail du produit anti-SLIT1 anticorps

Antigène: SLIT1 (Slit Homolog 1 (SLIT1))

Épitope: AA 487-504

Reactivité: Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SLIT1 est non-conjugé

Application: Western Blotting (WB), ELISA

Réactivité croisée: Rat (Rattus)

Attributs du produit: Concentration Definition: by UV absorbance at 280 nm

Immunogène: This affinity purified antibody was prepared from whole rabbit serum produced by repeated immunizations with a synthetic peptide corresponding aa 487-504 of mouse SLIT-1 protein.

Isotype: IgG

Information d'application

Indications d'application: This affinity purified antibody has been tested for use in ELISA and by western blot.  Specific conditions for reactivity should be optimized by the end user. Expect multiple bands corresponding to cleavage products of SLIT-1 by western blotting in the appropriate cell lysate or extract.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1.2 mg/mL

Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Détails sur SLIT1

Antigène: SLIT1 (Slit Homolog 1 (SLIT1))

Autre désignation: SLIT-1 (SLIT1 Produits)

Synonymes: anticorps Slil1, anticorps mKIAA0813, anticorps MEGF4, anticorps SLIL1, anticorps SLIT-1, anticorps SLIT3, anticorps megf4, anticorps slil1, anticorps slit-1, anticorps SLIT1, anticorps slit3, anticorps slit homolog 1 (Drosophila), anticorps slit guidance ligand 1, anticorps slit guidance ligand 1 S homeolog, anticorps slit homolog 1 protein, anticorps slit homolog 1b (Drosophila), anticorps slit homolog 1a (Drosophila), anticorps Slit1, anticorps SLIT1, anticorps slit1.S, anticorps slit1, anticorps LOC100459557, anticorps slit1b, anticorps slit1a

Sujet: SLIT-1 (also known as KIAA0813, MEGF4, multiple epidermal growth factor-like domains 4 and Slit homolog 1 protein) is a Slit protein.  This protein is a ligand for the Roundabout (Robo) receptors and acts as guidance cues in axonal migration/navigation during neural development, at the ventral midline of the neural tube. Slit1 and Slit2 are essential for midline guidance in the forebrain by acting as repulsive signals preventing inappropriate midline crossing by axons projecting from the olfactory bulb.  Each SLIT gene encodes a putative secreted protein, which contains conserved protein-protein interaction domains including leucine-rich repeats and epidermal growth factor-like motifs, similar to those of the Drosophila protein. In situ hybridization studies indicated that the rat SLIT-1 mRNA was specifically expressed in the neurons of fetal and adult forebrains. This data suggests that the SLIT genes form an evolutionarily conserved group in vertebrates and invertebrates, and that the mammalian SLIT proteins may participate in the formation and maintenance of the nervous and endocrine systems by protein-protein interactions.  Alternative splicing isoforms have been identified for Slit1 protein.
Synonyms: KIAA0813 antibody, MEGF 4 antibody, MEGF4 antibody, Multiple epidermal growth factor-like domains 4 antibody

ID gène: 20562, 256355216

UniProt: Q80TR4

Pathways: Regulation of Cell Size