CD200 anticorps (FITC)

N° du produit ABIN133412

Détail du produit anti-CD200 anticorps (FITC)

Antigène: CD200

Reactivité: Rat

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp CD200 est conjugé à/à la FITC

Application: Flow Cytometry (FACS)

Specificité: Rat thymocytes, brain, follicular dendritic cells in lymphoid organs, vascular endothelium, and at low levels on some smooth muscle and B lymphocytes

Purification: Purified from ascites via Protein G Chromatography

Clone: OX-2

Isotype: IgG1

Information d'application

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Concentration: 0.1 mg/ml

Buffer: FITC conjugated Ig buffered in PBS, 0.02% NaN and EIA grade BSA as a stabilizing protein to bring total protein concentration to 4-5 mg/ml.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Détails sur CD200

Antigène: CD200

Autre désignation: OX-2 (CD200 Produits)

Synonymes: anticorps MOX1, anticorps MOX2, anticorps MRC, anticorps OX-2, anticorps CD200, anticorps Cspmo2, anticorps MRCOX2, anticorps Mox2, anticorps DKFZp459C0716, anticorps OX2, anticorps CD200 molecule, anticorps Cd200 molecule, anticorps CD200 antigen, anticorps CD200, anticorps Cd200

Sujet: Mouse anti-rat OX-2 monoclonal antibody recognizes a monomorphic determinant present on rat thymocytes, brain, follicular dendritic cells in lymphoid organs, vascular endothelium, and at low levels on some smooth muscle and B lymphocytes. The purified brain and thymocyte OX-2 antigens are glycoproteins with apparent M.W. of 41 KDa and 47 KDa respectively. The amino acid composition of brain and thymocyte OX-2 antigen are very similar and are antigenically similar to those found on other tissues. The carbohydrate composition shows that this antigen is highly glycosylated (brain OX-2 - 24% and thymocyte OX-2 - 33% carbohydrate by weight). The OX-2 antigen shows similarities to the Thy-1 antigen in its odd pattern of tissue distribution, carbohydrate composition and characteristic migration on SDS- PAGE. Also, the OX-2 antigens, like Thy-1 antigens, have homologies with immunoglobulin domains the overall structure of OX-2 is similar to an Ig light chain or the T cell receptor chain. Because of its distribution, it is thought to play a role in mediating recognition events at cell surfaces. This clone can be used in flow cytometry, affinity chromatography, immunohistochemistry and in binding assays. It is also useful for labeling the follicular dendritic cells thought to be involved in the generation of B cell memory as it does not label the Ia-positive dendritic cells present in the T-dependant areas of lymphoid organs.