TNFRSF10B anticorps

N° du produit ABIN1383912

Détail du produit anti-TNFRSF10B anticorps

Antigène: TNFRSF10B (Tumor Necrosis Factor Receptor Superfamily, Member 10b (TNFRSF10B))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp TNFRSF10B est non-conjugé

Application: Flow Cytometry (FACS), ELISA, Functional Studies (Func)

Specificité: Recognises a 42-46 kDa protein

Purification: Ion exchange chromatography

Stérilité: 0.22 μm filtered

Immunogène: Recombinant human TRAIL R2/Fc chimera,Myeloma X63/AG.8653 x Balb/c spleen cells

Clone: B-K29

Isotype: IgG1 kappa

Biological Activity Comment: Neutralizes TRAIL induced apoptosis of U937 cell line

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Phosphate-buffered saline. Sterile-filtered through 0.22 μm. Carrier and preservative free

Agent conservateur: Without preservative

Stock: 4 °C

Stockage commentaire: Stable at +2-8°C for 12 months. For longer storage freeze aliquots.

Références pour anticorps anti-TNFRSF10B (ABIN1383912)

Chen, Chou, Chang, Chen: "Proteasome inhibitors enhance TRAIL-induced apoptosis through the intronic regulation of DR5: involvement of NF-kappa B and reactive oxygen species-mediated p53 activation." dans: Journal of immunology (Baltimore, Md. : 1950), Vol. 180, Issue 12, pp. 8030-9, (2008) (PubMed).

Sato, Niessner, Kopecky, Frye, Goronzy, Weyand: "TRAIL-expressing T cells induce apoptosis of vascular smooth muscle cells in the atherosclerotic plaque." dans: The Journal of experimental medicine, Vol. 203, Issue 1, pp. 239-50, (2006) (PubMed).

Vermot-Desroches, Sergent, Bonnin, Wijdenes: "Characterization of monoclonal antibodies directed against trail or trail receptors." dans: Cellular immunology, Vol. 236, Issue 1-2, pp. 86-91, (2005) (PubMed).

Détails sur TNFRSF10B

Antigène: TNFRSF10B (Tumor Necrosis Factor Receptor Superfamily, Member 10b (TNFRSF10B))

Autre désignation: TRAIL R2 (TNFRSF10B Produits)

Synonymes: anticorps TNFRSF10B, anticorps dr5, anticorps cd262, anticorps killer, anticorps trick2, anticorps trickb, anticorps xDR-M1, anticorps xDR-M2, anticorps ztnfr9, anticorps trailr2, anticorps trick2a, anticorps trick2b, anticorps CD262, anticorps DR5, anticorps KILLER, anticorps KILLER/DR5, anticorps TRAIL-R2, anticorps TRAILR2, anticorps TRICK2, anticorps TRICK2A, anticorps TRICK2B, anticorps TRICKB, anticorps ZTNFR9, anticorps Ly98, anticorps MK, anticorps tumor necrosis factor receptor superfamily, member 10b, anticorps tumor necrosis factor receptor superfamily member 10b S homeolog, anticorps tumor necrosis factor receptor superfamily member 10b L homeolog, anticorps tumor necrosis factor receptor superfamily member 10b, anticorps TNF receptor superfamily member 10b, anticorps Tnfrsf10b, anticorps TNFRSF10B, anticorps tnfrsf10b.S, anticorps tnfrsf10b.L, anticorps tnfrsf10b

Sujet: DR5, TRAIL R2

Poids moléculaire: 42-46 kDa

Pathways: Signalisation p53, Apoptose, Positive Regulation of Endopeptidase Activity