Tel:
+49 (0)241 95 163 153
Fax:
+49 (0)241 95 163 155
E-Mail:
orders@anticorps-enligne.fr

IL-6 anticorps

IL6 Reactivité: Humain ELISA, FACS, Func, ELISpot Hôte: Souris Monoclonal B-E8 unconjugated
N° du produit ABIN1383944
  • Antigène Voir toutes IL-6 (IL6) Anticorps
    IL-6 (IL6) (Interleukin 6 (IL6))
    Reactivité
    • 181
    • 135
    • 73
    • 28
    • 22
    • 21
    • 15
    • 13
    • 7
    • 6
    • 4
    • 3
    • 3
    • 3
    • 2
    Humain
    Hôte
    • 195
    • 83
    • 72
    • 13
    • 4
    • 3
    • 2
    Souris
    Clonalité
    • 215
    • 154
    • 1
    Monoclonal
    Conjugué
    • 199
    • 63
    • 27
    • 12
    • 11
    • 8
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp IL-6 est non-conjugé
    Application
    • 267
    • 138
    • 105
    • 61
    • 52
    • 50
    • 41
    • 41
    • 38
    • 31
    • 25
    • 25
    • 22
    • 19
    • 15
    • 8
    • 7
    • 6
    • 5
    • 5
    • 4
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    ELISA, Flow Cytometry (FACS), Functional Studies (Func), ELISpot
    Specificité
    Recognises both natural and recombinant human IL-6
    Purification
    Ion exchange chromatography
    Stérilité
    0.22 μm filtered
    Immunogène
    Recombinant human IL-6,Myeloma X63/AG.8653 x Balb/c spleen cells
    Clone
    B-E8
    Isotype
    IgG1 kappa
    Biological Activity Comment
    Inhibits IL-6 induced proliferation on XG1 Cell line
    Top Product
    Discover our top product IL6 Anticorps primaire
  • Indications d'application
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Phosphate-buffered saline. Sterile-filtered through 0.22 μm. Carrier and preservative free
    Agent conservateur
    Without preservative
    Stock
    4 °C
    Stockage commentaire
    Stable at +2-8°C for 12 months. For longer storage freeze aliquots.
  • Sprynski, Hose, Caillot, Réme, Shaughnessy, Barlogie, Seckinger, Moreaux, Hundemer, Jourdan, Meissner, Jauch, Mahtouk, Kassambara, Bertsch, Rossi, Goldschmidt, Klein: "The role of IGF-1 as a major growth factor for myeloma cell lines and the prognostic relevance of the expression of its receptor." dans: Blood, Vol. 113, Issue 19, pp. 4614-26, (2009) (PubMed).

    Adam, Rabe, Suthaus, Grötzinger, Rose-John, Scheller: "Unraveling viral interleukin-6 binding to gp130 and activation of STAT-signaling pathways independently of the interleukin-6 receptor." dans: Journal of virology, Vol. 83, Issue 10, pp. 5117-26, (2009) (PubMed).

    Moreau, Garban, Attal, Michallet, Marit, Hulin, Benboubker, Doyen, Mohty, Yakoub-Agha, Leyvraz, Casassus, Avet-Loiseau, Garderet, Mathiot, Harousseau: "Long-term follow-up results of IFM99-03 and IFM99-04 trials comparing nonmyeloablative allotransplantation with autologous transplantation in high-risk de novo multiple myeloma." dans: Blood, Vol. 112, Issue 9, pp. 3914-5, (2008) (PubMed).

    Garban, Attal, Michallet, Hulin, Bourhis, Yakoub-Agha, Lamy, Marit, Maloisel, Berthou, Dib, Caillot, Deprijck, Ketterer, Harousseau, Sotto, Moreau: "Prospective comparison of autologous stem cell transplantation followed by dose-reduced allograft (IFM99-03 trial) with tandem autologous stem cell transplantation (IFM99-04 trial) in high-risk de novo multiple myeloma." dans: Blood, Vol. 107, Issue 9, pp. 3474-80, (2006) (PubMed).

    Moreau, Hullin, Garban, Yakoub-Agha, Benboubker, Attal, Marit, Fuzibet, Doyen, Voillat, Berthou, Ketterer, Casassus, Monconduit, Michallet, Najman, Sotto, Bataille, Harousseau: "Tandem autologous stem cell transplantation in high-risk de novo multiple myeloma: final results of the prospective and randomized IFM 99-04 protocol." dans: Blood, Vol. 107, Issue 1, pp. 397-403, (2005) (PubMed).

    Song, Torphy, Griswold, Shealy: "Coming of age: anti-cytokine therapies." dans: Molecular interventions, Vol. 2, Issue 1, pp. 36-46, (2004) (PubMed).

    Moreaux, Legouffe, Jourdan, Quittet, Rème, Lugagne, Moine, Rossi, Klein, Tarte: "BAFF and APRIL protect myeloma cells from apoptosis induced by interleukin 6 deprivation and dexamethasone." dans: Blood, Vol. 103, Issue 8, pp. 3148-57, (2004) (PubMed).

    Derhaschnig, Bergmair, Marsik, Schlifke, Wijdenes, Jilma: "Effect of interleukin-6 blockade on tissue factor-induced coagulation in human endotoxemia." dans: Critical care medicine, Vol. 32, Issue 5, pp. 1136-40, (2004) (PubMed).

    Smith, Barg, Weedon, Papengelis, Smeets, Tak, Kraan, Coleman, Ahern: "Microarchitecture and protective mechanisms in synovial tissue from clinically and arthroscopically normal knee joints." dans: Annals of the rheumatic diseases, Vol. 62, Issue 4, pp. 303-7, (2003) (PubMed).

    Ancey, Menet, Corbi, Fredj, Garcia, Rücker-Martin, Bescond, Morel, Wijdenes, Lecron, Potreau: "Human cardiomyocyte hypertrophy induced in vitro by gp130 stimulation." dans: Cardiovascular research, Vol. 59, Issue 1, pp. 78-85, (2003) (PubMed).

    Choy: "Interleukin 6 receptor as a target for the treatment of rheumatoid arthritis." dans: Annals of the rheumatic diseases, Vol. 62 Suppl 2, pp. ii68-9, (2003) (PubMed).

    Derenne, Monia, Dean, Taylor, Rapp, Harousseau, Bataille, Amiot: "Antisense strategy shows that Mcl-1 rather than Bcl-2 or Bcl-x(L) is an essential survival protein of human myeloma cells." dans: Blood, Vol. 100, Issue 1, pp. 194-9, (2002) (PubMed).

    Delneste, Charbonnier, Herbault, Magistrelli, Caron, Bonnefoy, Jeannin: "Interferon-gamma switches monocyte differentiation from dendritic cells to macrophages." dans: Blood, Vol. 101, Issue 1, pp. 143-50, (2002) (PubMed).

    Leblond, Dhedin, Mamzer Bruneel, Choquet, Hermine, Porcher, Nguyen Quoc, Davi, Charlotte, Dorent, Barrou, Vernant, Raphael, Levy: "Identification of prognostic factors in 61 patients with posttransplantation lymphoproliferative disorders." dans: Journal of clinical oncology : official journal of the American Society of Clinical Oncology, Vol. 19, Issue 3, pp. 772-8, (2001) (PubMed).

    Jego, Bataille, Pellat-Deceunynck: "Interleukin-6 is a growth factor for nonmalignant human plasmablasts." dans: Blood, Vol. 97, Issue 6, pp. 1817-22, (2001) (PubMed).

    Menetrier-Caux, Thomachot, Alberti, Montmain, Blay: "IL-4 prevents the blockade of dendritic cell differentiation induced by tumor cells." dans: Cancer research, Vol. 61, Issue 7, pp. 3096-104, (2001) (PubMed).

    Corbellino, Bestetti, Scalamogna, Calattini, Galazzi, Meroni, Manganaro, Fasan, Moroni, Galli, Parravicini: "Long-term remission of Kaposi sarcoma-associated herpesvirus-related multicentric Castleman disease with anti-CD20 monoclonal antibody therapy." dans: Blood, Vol. 98, Issue 12, pp. 3473-5, (2001) (PubMed).

    Haddad, Paczesny, Leblond, Seigneurin, Stern, Achkar, Bauwens, Delwail, Debray, Duvoux, Hubert, Hurault de Ligny, Wijdenes, Durandy, Fischer: "Treatment of B-lymphoproliferative disorder with a monoclonal anti-interleukin-6 antibody in 12 patients: a multicenter phase 1-2 clinical trial." dans: Blood, Vol. 97, Issue 6, pp. 1590-7, (2001) (PubMed).

    Kube, Holtick, Vockerodt, Ahmadi, Haier, Behrmann, Heinrich, Diehl, Tesch: "STAT3 is constitutively activated in Hodgkin cell lines." dans: Blood, Vol. 98, Issue 3, pp. 762-70, (2001) (PubMed).

    Foussat, Wijdenes, Bouchet, Gaidano, Neipel, Balabanian, Galanaud, Couderc, Emilie: "Human interleukin-6 is in vivo an autocrine growth factor for human herpesvirus-8-infected malignant B lymphocytes." dans: European cytokine network, Vol. 10, Issue 4, pp. 501-8, (2000) (PubMed).

  • Antigène
    IL-6 (IL6) (Interleukin 6 (IL6))
    Autre désignation
    IL-6 (IL6 Produits)
    Synonymes
    anticorps BSF2, anticorps HGF, anticorps HSF, anticorps IFNB2, anticorps IL-6, anticorps Il-6, anticorps ILg6, anticorps Ifnb2, anticorps il6, anticorps CHIL-6, anticorps interleukin 6, anticorps interleukin-6, anticorps IL6, anticorps Il6, anticorps il-6, anticorps IL-6
    Pathways
    Signalisation TLR, Hormone Transport, Negative Regulation of Hormone Secretion, Myometrial Relaxation and Contraction, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Regulation of Carbohydrate Metabolic Process, Autophagy, Cell RedoxHomeostasis, Cancer Immune Checkpoints, Inflammasome
Vous êtes ici:
Support technique