MPP5 anticorps (AA 201-300)
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- Antigène Voir toutes MPP5 Anticorps
- MPP5 (Membrane Protein, Palmitoylated 5 (MAGUK P55 Subfamily Member 5) (MPP5))
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Épitope
- AA 201-300
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Reactivité
- Humain
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp MPP5 est non-conjugé
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Application
- Western Blotting (WB), ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC), Immunohistochemistry (Frozen Sections) (IHC (fro))
- Homologie
- Human,Mouse,Rat,Dog,Cow,Sheep,Pig,Horse,Chicken,Rabbit
- Purification
- Purified by Protein A.
- Immunogène
- KLH conjugated synthetic peptide derived from human MPP5/PALS1
- Isotype
- IgG
- Top Product
- Discover our top product MPP5 Anticorps primaire
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- Indications d'application
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WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500 - Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 μg/μL
- Buffer
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
- Agent conservateur
- ProClin
- Précaution d'utilisation
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Stock
- 4 °C,-20 °C
- Stockage commentaire
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
- Date de péremption
- 12 months
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- Antigène
- MPP5 (Membrane Protein, Palmitoylated 5 (MAGUK P55 Subfamily Member 5) (MPP5))
- Autre désignation
- MPP5/PALS1 (MPP5 Produits)
- Synonymes
- anticorps PALS1, anticorps 3830420B02Rik, anticorps AI255216, anticorps AI644496, anticorps Pals1, anticorps mpp5, anticorps nok, anticorps MAGUK p55 subfamily member 5, anticorps membrane palmitoylated protein 5, anticorps membrane protein, palmitoylated 5 L homeolog, anticorps membrane protein, palmitoylated 5 (MAGUK p55 subfamily member 5), anticorps membrane protein, palmitoylated 5a (MAGUK p55 subfamily member 5), anticorps Tsp_03061, anticorps MPP5, anticorps mpp5.L, anticorps Mpp5, anticorps mpp5a
- Sujet
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Synonyms: FLJ12615, MAGUK p55 subfamily member 5, Membrane protein palmitoylated 5, MPP 5, MPP5, MPP5_HUMAN, PALS 1, PALS1, Protein associated with Lin-7, Stardust Drosophila, Stardust.
Background: Two highly conserved complexes are responsible for the assembly of tight junctions, the Crumbs-Pals1-Patj complex and the Cdc42-Par6-Par3-aPKC complex. Tight junctions assist in the formation of polarity in the epithelia by establishing a barrier to separate apical and basolateral membranes. Pals1, importantly, mediates interaction between the two complexes via interaction with Par6. Loss of Pals1 function results in delayed polarization, decreased transepithelial electrical resistance and an inability to form lumenal cysts. Because tumors exhibit perturbations in epithelial polarity, Pals1 presents a new potential target in the study of carcinogenesis.
- Pathways
- Nucleotide Phosphorylation, Tube Formation, Asymmetric Protein Localization
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