CD276 anticorps (AA 101-200) (Alexa Fluor 647)
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- Antigène Voir toutes CD276 Anticorps
- CD276
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Épitope
- AA 101-200
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Reactivité
- Humain, Souris
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp CD276 est conjugé à/à la Alexa Fluor 647
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Application
- Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunofluorescence (Cultured Cells) (IF (cc))
- Réactivité croisée
- Humain, Souris
- Homologie
- Rat,Cow,Pig,Horse
- Purification
- Purified by Protein A.
- Immunogène
- KLH conjugated synthetic peptide derived from human CD276/B7H3
- Isotype
- IgG
- Top Product
- Discover our top product CD276 Anticorps primaire
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- Indications d'application
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- Agent conservateur
- ProClin
- Précaution d'utilisation
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Stock
- -20 °C
- Stockage commentaire
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- Date de péremption
- 12 months
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- Antigène
- CD276
- Autre désignation
- CD276/B7H3 (CD276 Produits)
- Synonymes
- anticorps sc:d0645, anticorps zgc:158279, anticorps 6030411F23Rik, anticorps AU016588, anticorps B7RP-2, anticorps B7h3, anticorps B7H3, anticorps 4Ig-B7-H3, anticorps B7-H3, anticorps CD276 molecule, anticorps CD276 molecule S homeolog, anticorps CD276 antigen, anticorps Cd276 molecule, anticorps CD276, anticorps cd276.S, anticorps cd276, anticorps Cd276
- Sujet
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Synonyms: B7H3, B7-H3, B7RP-2, 4Ig-B7-H3, CD276 antigen, B7 homolog 3, Costimulatory molecule, CD276, PSEC0249, UNQ309/PRO352
Background: May participate in the regulation of T-cell-mediated immune response. May play a protective role in tumor cells by inhibiting natural-killer mediated cell lysis as well as a role of marker for detection of neuroblastoma cells. May be involved in the development of acute and chronic transplant rejection and in the regulation of lymphocytic activity at mucosal surfaces. Could also play a key role in providing the placenta and fetus with a suitable immunological environment throughout pregnancy. Both isoform 1 and isoform 2 appear to be redundant in their ability to modulate CD4 T-cell responses. Isoform 2 is shown to enhance the induction of cytotoxic T-cells and selectively stimulates interferon gamma production in the presence of T-cell receptor signaling.
- ID gène
- 80381
- UniProt
- Q5ZPR3
- Pathways
- Cancer Immune Checkpoints
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