MPP5 anticorps (AA 201-300) (Biotin)

N° du produit ABIN1393915

Détail du produit anti-MPP5 anticorps (Biotin)

Antigène: MPP5 (Membrane Protein, Palmitoylated 5 (MAGUK P55 Subfamily Member 5) (MPP5))

Épitope: AA 201-300

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MPP5 est conjugé à/à la Biotin

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Homologie: Human,Mouse,Rat,Dog,Cow,Sheep,Pig,Horse,Chicken,Rabbit

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human MPP5/PALS1

Isotype: IgG

Information d'application

Indications d'application: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C for 12 months.

Date de péremption: 12 months

Détails sur MPP5

Antigène: MPP5 (Membrane Protein, Palmitoylated 5 (MAGUK P55 Subfamily Member 5) (MPP5))

Autre désignation: MPP5/PALS1 (MPP5 Produits)

Synonymes: anticorps PALS1, anticorps 3830420B02Rik, anticorps AI255216, anticorps AI644496, anticorps Pals1, anticorps mpp5, anticorps nok, anticorps MAGUK p55 subfamily member 5, anticorps membrane palmitoylated protein 5, anticorps membrane protein, palmitoylated 5 L homeolog, anticorps membrane protein, palmitoylated 5 (MAGUK p55 subfamily member 5), anticorps membrane protein, palmitoylated 5a (MAGUK p55 subfamily member 5), anticorps Tsp_03061, anticorps MPP5, anticorps mpp5.L, anticorps Mpp5, anticorps mpp5a

Sujet:

Synonyms: FLJ12615, MAGUK p55 subfamily member 5, Membrane protein palmitoylated 5, MPP 5, MPP5, MPP5_HUMAN, PALS 1, PALS1, Protein associated with Lin-7, Stardust Drosophila, Stardust.

Background: Two highly conserved complexes are responsible for the assembly of tight junctions, the Crumbs-Pals1-Patj complex and the Cdc42-Par6-Par3-aPKC complex. Tight junctions assist in the formation of polarity in the epithelia by establishing a barrier to separate apical and basolateral membranes. Pals1, importantly, mediates interaction between the two complexes via interaction with Par6. Loss of Pals1 function results in delayed polarization, decreased transepithelial electrical resistance and an inability to form lumenal cysts. Because tumors exhibit perturbations in epithelial polarity, Pals1 presents a new potential target in the study of carcinogenesis.

Pathways: Nucleotide Phosphorylation, Tube Formation, Asymmetric Protein Localization