MUC1 anticorps (AA 941-1040) (Alexa Fluor 647)
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- Antigène Voir toutes MUC1 Anticorps
- MUC1 (Mucin 1 (MUC1))
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Épitope
- AA 941-1040
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Reactivité
- Humain
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp MUC1 est conjugé à/à la Alexa Fluor 647
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Application
- Western Blotting (WB), Flow Cytometry (FACS)
- Réactivité croisée
- Humain
- Purification
- Purified by Protein A.
- Immunogène
- KLH conjugated synthetic peptide derived from human MUC1
- Isotype
- IgG
- Top Product
- Discover our top product MUC1 Anticorps primaire
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- Indications d'application
- FCM 1:20-100
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- Agent conservateur
- ProClin
- Précaution d'utilisation
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Stock
- -20 °C
- Stockage commentaire
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- Date de péremption
- 12 months
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- Antigène
- MUC1 (Mucin 1 (MUC1))
- Autre désignation
- MUC1 (MUC1 Produits)
- Synonymes
- anticorps CA 15-3, anticorps CD227, anticorps EMA, anticorps H23AG, anticorps KL-6, anticorps MAM6, anticorps MCKD1, anticorps MUC-1, anticorps MUC-1/SEC, anticorps MUC-1/X, anticorps MUC1/ZD, anticorps PEM, anticorps PEMT, anticorps PUM, anticorps Muc-1, anticorps mucin 1, cell surface associated, anticorps mucin 1, transmembrane, anticorps MUC1, anticorps Muc1
- Sujet
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Synonyms: Breast carcinoma associated antigen DF3, Breast carcinoma associated antigen DF3, Breast carcinoma-associated antigen DF3, CA 15 3, CA 15-3, CA15 3, CA15 3 antigen, CA15.3, Cancer antigen 15-3, Carcinoma associated mucin, Carcinoma associated mucin, Carcinoma-associated mucin, CD 227, CD227, CD227, CD227 antigen, DF3 antigen, DF3 antigen, EMA, EMA, Episialin, Episialin, Epithelial membrane antigen, Epithelial membrane antigen, Epithelial mucin tandem repeat sequence, H23 antigen, H23 antigen, H23AG, H23AG, HGNC:7508, KL 6, KL-6, KL6, Krebs von den Lungen-6, MAM 6, MAM6, MUC 1, MUC 1, MUC-1, MUC-1/SEC, MUC-1/X, MUC1, MUC1-alpha, MUC1-beta, MUC1-CT, MUC1-NT, MUC1/ZD, MUC1_HUMAN, Mucin 1, Mucin 1 precursor, Mucin 1 transmembrane, Mucin-1 subunit beta, Mucin1, Mucin1, Peanut reactive urinary mucin, Peanut reactive urinary mucin, Peanut-reactive urinary mucin, PEM, PEMT, PEMT, Polymorphic epithelial mucin, Polymorphic epithelial mucin, PUM, PUM, Tumor associated epithelial membrane antigen, Tumor associated epithelial membrane antigen, Tumor associated epithelial mucin, Tumor associated mucin, Tumor associated mucin, Tumor-associated epithelial membrane antigen, Tumor-associated mucin.
Background: MUC1 is a large cell surface mucin glycoprotein expressed by most glandular and ductal epithelial cells and some hematopoietic cell lineages. It is expressed on most secretory epithelium, including mammary gland and some hematopoietic cells. It is expressed abundantly in lactating mammary glands and overexpressed abundantly in >90 % breast carcinomas and metastases. Transgenic MUC1 has been shown to associate with all four cebB receptors and localize with erbB1 (EGFR) in lactating glands. The MUC1 gene contains seven exons and produces several different alternatively spliced variants. The major expressed form of MUC1 uses all seven exons and is a type 1 transmembrane protein with a large extracellular tandem repeat domain. The tandem repeat domain is highly O glycosylated and alterations in glycosylation have been shown in epithelial cancer cells.
- ID gène
- 4582
- Pathways
- Negative Regulation of intrinsic apoptotic Signaling
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