MSH3 anticorps (AA 651-750) (Alexa Fluor 555)

N° du produit ABIN1399625

Détail du produit anti-MSH3 anticorps (Alexa Fluor 555)

Antigène: MSH3 (MutS Homolog 3 (MSH3))

Épitope: AA 651-750

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MSH3 est conjugé à/à la Alexa Fluor 555

Application: Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunofluorescence (Cultured Cells) (IF (cc))

Homologie: Human,Mouse,Rat,Dog,Cow,Rabbit

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human MSH3

Isotype: IgG

Information d'application

Indications d'application: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Date de péremption: 12 months

Détails sur MSH3

Antigène: MSH3 (MutS Homolog 3 (MSH3))

Autre désignation: MSH3 (MSH3 Produits)

Synonymes: anticorps ATMSH3, anticorps M7J2.90, anticorps M7J2_90, anticorps homolog of DNA mismatch repair protein MSH3, anticorps DUP, anticorps MRP1, anticorps D13Em1, anticorps Rep-3, anticorps Rep3, anticorps mutS homolog 3, anticorps DNA mismatch repair protein MSH3, anticorps homolog of DNA mismatch repair protein MSH3, anticorps mismatch repair protein, anticorps MSH3, anticorps Msh3

Sujet:

Synonyms: Divergent upstream protein, DNA mismatch repair protein, DNA mismatch repair protein Msh 3, DNA mismatch repair protein Msh3, DUC 1, DUC1, DUG, DUP, hMSH3, Mismatch repair protein 1, MRP 1, MRP1, MSH 3, MSH-3, MSH3_HUMAN, MutS homolog 3.

Background: Component of the post-replicative DNA mismatch repair system (MMR). Heterodimerizes with MSH2 to form MutS beta which binds to DNA mismatches thereby initiating DNA repair. When bound, the MutS beta heterodimer bends the DNA helix and shields approximately 20 base pairs. MutS beta recognizes large insertion-deletion loops (IDL) up to 13 nucleotides long. After mismatch binding, forms a ternary complex with the MutL alpha heterodimer, which is thought to be responsible for directing the downstream MMR events, including strand discrimination, excision, and resynthesis.

ID gène: 4437

Pathways: Réparation de l'ADN, Production of Molecular Mediator of Immune Response