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RAB17 anticorps (AA 101-200) (Cy5.5)

RAB17 Reactivité: Humain WB, IF (cc), IF (p) Hôte: Lapin Polyclonal Cy5.5
N° du produit ABIN1408013
  • Antigène Voir toutes RAB17 Anticorps
    RAB17 (RAB17, Member RAS Oncogene Family (RAB17))
    Épitope
    • 14
    • 8
    • 7
    • 6
    • 6
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 101-200
    Reactivité
    • 33
    • 27
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Humain
    Hôte
    • 43
    • 3
    • 1
    Lapin
    Clonalité
    • 44
    • 3
    Polyclonal
    Conjugué
    • 17
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp RAB17 est conjugé à/à la Cy5.5
    Application
    • 40
    • 23
    • 12
    • 12
    • 6
    • 5
    • 3
    • 3
    • 3
    Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
     Réactivité croisée
    Humain
    Homologie
    Mouse,Rat,Dog
    Purification
    Purified by Protein A.
    Immunogène
    KLH conjugated synthetic peptide derived from human Rab17
    Isotype
    IgG
    Top Product
    Discover our top product RAB17 Anticorps primaire
  • Indications d'application
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Agent conservateur
    ProClin
    Précaution d'utilisation
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    Date de péremption
    12 months
  • Antigène
    RAB17 (RAB17, Member RAS Oncogene Family (RAB17))
    Autre désignation
    Rab17 (RAB17 Produits)
    Synonymes
    anticorps RAB17, anticorps AW413472, anticorps RGD1562478, anticorps rab17, anticorps RAB17, member RAS oncogene family, anticorps EDI_278050, anticorps EDI_260720, anticorps EDI_050010, anticorps RAB17, anticorps Rab17
    Sujet

    Synonyms: Rab 17, Rab17, RAB17 member RAS oncogene family, RAB17_HUMAN, Ras related protein Rab 17, Ras related protein Rab17, Ras-related protein Rab-17, FLJ12538, OTTHUMP00000164417, OTTHUMP00000202805.

    Background: Rab17 belongs to the Rab family of small Ras-like GTPases. It is specifically expressed in epithelial cells and is upregulated during cell polarization. Immunofluorescence staining studies indicate that Rab17 is associated with the perinuclear recycling endosome in nonpolarized epithelial cells and with the apical recycling endosome in polarized epithelial cells. The function of Rab17 remains unclear. Reports of Rab17 colocalization with internalized IgA in the apical endosome suggest that it may regulate receptor-mediated transcytosis. Rab17 has also been shown to regulate melanocytic filopodia formation and melanosome trafficking. siRNA knockdown of Rab17 in melanoma cells induces melanosome accumulation in the cell periphery.

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