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Endothelin 2 anticorps (AA 49-59) (Cy5.5)

EDN2 Reactivité: Cat IF (cc), IF (p) Hôte: Lapin Polyclonal Cy5.5
N° du produit ABIN1408223
  • Antigène Voir toutes Endothelin 2 (EDN2) Anticorps
    Endothelin 2 (EDN2)
    Épitope
    • 14
    • 8
    • 7
    • 6
    • 6
    • 2
    • 2
    • 1
    AA 49-59
    Reactivité
    • 41
    • 14
    • 5
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    Cat
    Hôte
    • 52
    • 3
    Lapin
    Clonalité
    • 53
    • 2
    Polyclonal
    Conjugué
    • 20
    • 5
    • 4
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp Endothelin 2 est conjugé à/à la Cy5.5
    Application
    • 24
    • 20
    • 12
    • 12
    • 8
    • 5
    • 4
    • 4
    • 4
    • 3
    • 3
    • 3
    • 1
    • 1
    Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
     Réactivité croisée
    Cat
    Homologie
    Human,Mouse,Rat,Dog,Cow,Cat,Rabbit
    Purification
    Purified by Protein A.
    Immunogène
    KLH conjugated synthetic peptide derived from human Endolin 2
    Isotype
    IgG
    Top Product
    Discover our top product EDN2 Anticorps primaire
  • Indications d'application
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Agent conservateur
    ProClin
    Précaution d'utilisation
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    Date de péremption
    12 months
  • Antigène
    Endothelin 2 (EDN2)
    Autre désignation
    ET-2/Endothelin 2 (EDN2 Produits)
    Synonymes
    anticorps endothelin-2, anticorps EDN2, anticorps si:ch211-202b2.2, anticorps ET2, anticorps PPET2, anticorps VIC, anticorps Et2, anticorps ET-2, anticorps endothelin 2, anticorps EDN2, anticorps edn2, anticorps Edn2
    Sujet

    Synonyms: EDN2, EDN2_HUMAN, Endothelin 2, Endothelin-2, ET 2, ET-2, ET2, PPET2, Preproendothelin 2, Preproendothelin-2.

    Background: The endothelin (ET) family of proteins, which includes ET-1 (endothelin-1), ET-2 (endothelin-2) and ET-3 (endothelin-3), are vasoactive peptides that are involved in various functions throughout the body. Endothelins can affect the central nervous system and neuronal excitability, and they elicit potent vasoconstrictor action. While ET-1 is a potent, 21-amino acid vasoconstrictor peptide, ET-2 has the most potent vasoconstrictor activity. ET-3 functions as a ligand for endothelin receptor type B (ETBR) and, through this interaction, mediates the maturation of enteric neurons and melanocytes. Although ET-3 is expressed as a 238 amino acid peptide, it is post-translationally modified to produce a short active isoform and a long inactive isoform. Defects in the gene encoding ET-3 are the cause of a variety of disorders, including Hirschsprung disease type 1 (HSCR1), congenital central hypoventilation syndrome (CCHS) and Waardenburg syndrome type IV (WS4).

    Pathways
    Hormone Activity, Negative Regulation of Hormone Secretion, Regulation of Systemic Arterial Blood Pressure by Hormones
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