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HSD17B8 anticorps (AA 174-220) (Cy5.5)

HSD17B8 Reactivité: Souris WB, IF (cc), IF (p) Hôte: Lapin Polyclonal Cy5.5
N° du produit ABIN1408985
  • Antigène Voir toutes HSD17B8 Anticorps
    HSD17B8 (Hydroxysteroid (17-Beta) Dehydrogenase 8 (HSD17B8))
    Épitope
    • 14
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 174-220
    Reactivité
    • 25
    • 23
    • 9
    • 1
    Souris
    Hôte
    • 34
    • 5
    Lapin
    Clonalité
    • 29
    • 10
    Polyclonal
    Conjugué
    • 12
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp HSD17B8 est conjugé à/à la Cy5.5
    Application
    • 24
    • 12
    • 12
    • 6
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
     Réactivité croisée
    Souris
    Homologie
    Human,Rat,Rabbit
    Purification
    Purified by Protein A.
    Immunogène
    KLH conjugated synthetic peptide derived from human HSD17B8
    Isotype
    IgG
    Top Product
    Discover our top product HSD17B8 Anticorps primaire
  • Indications d'application
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Agent conservateur
    ProClin
    Précaution d'utilisation
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    Date de péremption
    12 months
  • Antigène
    HSD17B8 (Hydroxysteroid (17-Beta) Dehydrogenase 8 (HSD17B8))
    Autre désignation
    HSD17B8 (HSD17B8 Produits)
    Synonymes
    anticorps KE6, anticorps fabgl, anticorps zgc:112550, anticorps si:dz12f11.4, anticorps HKE6, anticorps FABGL, anticorps ke6, anticorps fabg, anticorps hke6, anticorps ring2, anticorps h2-ke6, anticorps d6s2245e, anticorps D17H6S112E, anticorps H-2Ke6, anticorps Hsd17b8, anticorps Ke-6, anticorps Ke6, anticorps Ring2, anticorps D6S2245E, anticorps FABG, anticorps H2-KE6, anticorps RING2, anticorps SDR30C1, anticorps dJ1033B10.9, anticorps Fabgl, anticorps hydroxysteroid (17-beta) dehydrogenase 8, anticorps hydroxysteroid 17-beta dehydrogenase 8, anticorps H2-K region expressed gene 6, anticorps hsd17b8, anticorps HSD17B8, anticorps H2-Ke6, anticorps Hsd17b8
    Sujet

    Synonyms: 17 beta HSD 8, 17 beta hydroxysteroid dehydrogenase 8, 17-beta-HSD 8, 17-beta-hydroxysteroid dehydrogenase 8, 3-oxoacyl-[acyl-carrier-protein] reductase, Beta ketoacyl [acyl carrier protein] reductase like, D6S2245E, DHB8_HUMAN, dJ1033B10.9, Estradiol 17 beta dehydrogenase 8, Estradiol 17-beta-dehydrogenase 8, Estrogen 17 oxidoreductase, FABG, FABGL, H2 KE6, HKE6, HSD17B8, Hydroxysteroid 17 beta dehydrogenase 8, 17beta hydroxysteroid dehydrogenase type 8, Ke-6, KE6, Protein Ke6, Really interesting new gene 2 protein, RING2, SDR30C1, Short chain dehydrogenase/reductase family 30C member 1, Testosterone 17 beta dehydrogenase 8, Testosterone 17-beta-dehydrogenase 8.

    Background: 17beta-HSD8 belongs to the 17beta-HSD family of proteins that regulate the availability of steroids within a tissue. 17beta-HSD8 converts active steroids to their inactive form through its oxidative activity. It is a key player in the inactivation of Estradiol and Testosterone. 17beta-HSD8 is predominantly expressed in placenta, endometrium and prostate but can also be found in liver, and pancreas, with lowest levels found in testis, ovary and kidney. It has been proposed that a reduction in the levels of 17beta-HSD8 may lead to abnormal elevations in the local level of sex steroids, which can lead to recessive renal cystic disease. It has also been suggested that low levels of 17beta-HSD proteins may result in an underdeveloped urogenital system.

    ID gène
    7923
    Pathways
    Steroid Hormone Biosynthesis
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