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CADPS2 anticorps (AA 435-510) (Cy5.5)

CADPS2 Reactivité: Humain IF (cc), IF (p) Hôte: Lapin Polyclonal Cy5.5
N° du produit ABIN1409525
  • Antigène Voir toutes CADPS2 Anticorps
    CADPS2 (Ca++-Dependent Secretion Activator 2 (CADPS2))
    Épitope
    • 14
    • 1
    • 1
    • 1
    AA 435-510
    Reactivité
    • 17
    • 2
    • 1
    Humain
    Hôte
    • 17
    Lapin
    Clonalité
    • 17
    Polyclonal
    Conjugué
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp CADPS2 est conjugé à/à la Cy5.5
    Application
    • 12
    • 12
    • 4
    • 3
    • 3
    • 1
    • 1
    • 1
    Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
    Homologie
    Human,Mouse,Rat,Dog,Cow,Sheep,Pig,Horse
    Purification
    Purified by Protein A.
    Immunogène
    KLH conjugated synthetic peptide derived from human CADPS2
    Isotype
    IgG
    Top Product
    Discover our top product CADPS2 Anticorps primaire
  • Indications d'application
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Agent conservateur
    ProClin
    Précaution d'utilisation
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    Date de péremption
    12 months
  • Antigène
    CADPS2 (Ca++-Dependent Secretion Activator 2 (CADPS2))
    Autre désignation
    CADPS2 (CADPS2 Produits)
    Synonymes
    anticorps RGD1559440, anticorps A230044C21Rik, anticorps Caps-2, anticorps Caps2, anticorps Cpd2, anticorps caps, anticorps cpd2, anticorps zgc:110135, anticorps calcium dependent secretion activator 2, anticorps Ca2+-dependent activator protein for secretion 2, anticorps Ca++-dependent secretion activator 2, anticorps CADPS2, anticorps Cadps2, anticorps cadps2
    Sujet

    Synonyms: Cadps2, Calcium-dependent activator protein for secretion 2, Calcium-dependent secretion activator 2, CAPS2, CAPS2_HUMAN.

    Background: Calcium-dependent secretion activators (CAPS-1 and CAPS-2) are calcium-binding proteins that direct neurotransmitter and neuropeptide-filled vesicles to the cell membrane for secretory granule exocytosis. Both CAPS-1 and CAPS-2 are expressed primarily in the brain where they regulate the secretion of various substances. The CAPS proteins contain a PH domain that is essential for regulation of exocytosis, as well as regulation of phospholipid binding. Through their regulation of neurotrophin release from granule cells, CAPS proteins help to regulate cell fate during neuronal development. CAPS-1 is thought to regulate catecholamine release from neuronal cells, while CAPS-2 is thought to regulate release of both brain-derived neurotrophic factor and neurotrophin-3 from granule cells. Defects in the genes encoding CAPS-1 and CAPS-2 are implicated in impaired cerebral development and autism.

    Pathways
    Synaptic Vesicle Exocytosis
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