P-Selectin anticorps (APC)

N° du produit ABIN1449147

Détail du produit anti-P-Selectin anticorps (APC)

Antigène: P-Selectin (SELP) (Selectin P (Granule Membrane Protein 140kDa, Antigen CD62) (SELP))

Reactivité: Humain, Primate

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp P-Selectin est conjugé à/à la APC

Application: Flow Cytometry (FACS)

Réactivité croisée (Details): Species reactivity (tested):Human, Primates

Immunogène: Human platelets

Clone: AK4

Isotype: IgG1

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Buffer: Phosphate buffered saline (PBS), 15 mM sodium azide, 0.2 % (w/v) high-grade protease free Bovine Serum Albumin (BSA)

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: DO NOT FREEZE! This products is photosensitive and should be protected from light.

Stock: 4 °C

Stockage commentaire: Store undiluted at 2-8 °C.

Détails sur P-Selectin

Antigène: P-Selectin (SELP) (Selectin P (Granule Membrane Protein 140kDa, Antigen CD62) (SELP))

Autre désignation: CD62P / P-Selectin (SELP Produits)

Synonymes: anticorps PSELECT, anticorps CD62, anticorps CD62P, anticorps GMP140, anticorps GRMP, anticorps LECAM3, anticorps PADGEM, anticorps PSEL, anticorps GMP-140, anticorps Grmp, anticorps selectin P, anticorps selectin, platelet, anticorps Selp, anticorps SELP

Sujet: CD62P (P-selectin) is an adhesion glycoprotein that is expressed on platelets and endothelial cells upon their activation. Interaction between CD62P and its mucin-like ligand PSGL-1 (P-selectin glycoprotein ligand-1) expressed on the microvilli of most leukocytes supports leukocyte rolling along postkapillary venules at the earliest time of inflammation. Both CD62P and PSGL-1 are extended glycoproteins that form homodimers. CD62P dimerization is probably mediated through interactions of the transmembrane domains and stabilizes leukocyte tethering and rolling, probably by increasing rebinding within a bond cluster.Synonyms: CD62 antigen-like family member P, GMP-140, GMRP, GRMP, Granule membrane protein 140, LECAM3, Leukocyte-endothelial cell adhesion molecule 3, PADGEM, SELP

ID gène: 6403

NCBI Accession: NP_002996

UniProt: P16109