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SHANK3 anticorps (Middle Region)
SHANK3
Reactivité: Humain, Souris
WB, IF, IHC (p), EIA
Hôte: Lapin
Polyclonal
unconjugated
N° du produit ABIN1449931
Détail du produit anti-SHANK3 anticorps
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Antigène
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SHANK3
(SH3 and Multiple Ankyrin Repeat Domains 3 (SHANK3))
Épitope
Tous les épitopes à travers SHANK3 Anticorps.
Middle Region
Reactivité
Toutes les réactivités sur SHANK3 Anticorps
Humain, Souris
Hôte
Toutes les hôtes sur SHANK3 Anticorps
Lapin
Clonalité
Toutes les clonalités sur SHANK3 Anticorps
Polyclonal
Conjugué
Tous les conjugués à travers SHANK3 Anticorps
Cet anticorp SHANK3 est non-conjugé
Application
Tous les applications à travers SHANK3 Anticorps.
Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
Réactivité croisée (Details)
Species reactivity (tested):Human, Mouse.
Purification
Affinity chromatography purified via peptide column
Immunogène
19 amino acid synthetic peptide near the center of human SHANK3
Isotype
IgG
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Alternatives
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Information d'application
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Indications d'application
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Stockage
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Concentration
1.0 mg/mL
Buffer
PBS containing 0.02 % Sodium Azide as preservative
Agent conservateur
Sodium azide
Précaution d'utilisation
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Conseil sur la manipulation
Avoid repeated freezing and thawing.
Stock
4 °C/-20 °C
Stockage commentaire
Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Détails sur SHANK3
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Antigène
SHANK3
(SH3 and Multiple Ankyrin Repeat Domains 3 (SHANK3))
Autre désignation
SHANK3 (SHANK3 Produits )
Synonymes
anticorps DEL22q13.3, anticorps PROSAP2, anticorps PSAP2, anticorps SCZD15, anticorps SPANK-2, anticorps Prosap2, anticorps AI841104, anticorps Shank3b, anticorps SH3 and multiple ankyrin repeat domains 3, anticorps SH3 and multiple ankyrin repeat domains protein 3, anticorps SHANK3, anticorps shank3, anticorps Shank3
Sujet
SH3 and multiple ankyrin repeat domains 3 (SHANK3), a member of the Shank gene family, plays a role in synapse formation and dendritic spine maturation. Shank proteins (Shank 1-3) containing PDZ domains are scaffold proteins of the postsynaptic density (PSD) that connect neurotransmitter receptors and ion channels proteins to the actin cytoskeleton and G-protein-coupled signaling pathways. Transcript splice variation in the Shank family influences the spectrum of Shank-interacting proteins in the PSDs of adult and developing brain to ensure normal development. Mutations of SHANK3 are a cause of autism spectrum disorder (ASD) and the neurological symptoms of 22q13.3 deletion syndrome.Synonyms: PSAP2, ProSAP2, Proline-rich synapse-associated protein 2, SH3 and multiple ankyrin repeat domains 3, SPANK-2
NCBI Accession
NP_001073889
Pathways
Synaptic Membrane , Tube Formation , Regulation of long-term Neuronal Synaptic Plasticity
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