LZTS2 anticorps (N-Term)

N° du produit ABIN1450106

Détail du produit anti-LZTS2 anticorps

Antigène: LZTS2 (Leucine Zipper, Putative Tumor Suppressor 2 (LZTS2))

Épitope: N-Term

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp LZTS2 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Réactivité croisée (Details): Species reactivity (tested):Human, Mouse

Purification: Affinity chromatography purified via peptide column

Immunogène: A 19 amino acid synthetic peptide near the amino terminus of human LZTS2

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: PBS containing 0.02 % Sodium Azide as preservative

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur LZTS2

Antigène: LZTS2 (Leucine Zipper, Putative Tumor Suppressor 2 (LZTS2))

Autre désignation: LZTS2 (LZTS2 Produits)

Synonymes: anticorps lapser1, anticorps MGC89253, anticorps si:dkey-250a11.1, anticorps LAPSER1, anticorps BC014695, anticorps mKIAA1813, anticorps Lapser1, anticorps leucine zipper, putative tumor suppressor 2, anticorps leucine zipper tumor suppressor 2, anticorps leucine zipper, putative tumor suppressor 2a, anticorps leucine zipper, putative tumor suppressor 2 S homeolog, anticorps lzts2, anticorps LZTS2, anticorps lzts2a, anticorps Lzts2, anticorps lzts2.S

Sujet: The leucine zipper putative tumor suppressor 2 (LZTS2, also known as LAPSER1), a member of the LZTS family, is a negative regulator of the Wnt signaling pathway. It represses beta-catenin-mediated transcriptional activation by promoting the nuclear exclusion of beta-catenin. LZTS2 is involved in cytokinesis and regulates katanin-mediated microtubule severing and release from the centrosome. LZTS2 may negatively regulate axonal outgrowth by preventing the formation of microtubule bundles that are necessary for transport within the elongating axon. LZTS2 is highly expressed in testis and prostate, but it is deleted in multiple cancers, including prostate tumors, suggesting that LZTS2 acts as a potential tumor suppressor.Synonyms: KIAA1813, LAPSER1, LZTS2, Leucine zipper putative tumor suppressor 2, hLZTS2

ID gène: 84445

NCBI Accession: NP_115805