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Nephrin anticorps (Middle Region)
NPHS1
Reactivité: Humain
IHC (p), EIA
Hôte: Lapin
Polyclonal
unconjugated
N° du produit ABIN1450160
Détail du produit anti-Nephrin anticorps
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Antigène
Voir toutes Nephrin (NPHS1) Anticorps
Nephrin (NPHS1)
(Nephrosis 1, Congenital, Finnish Type (Nephrin) (NPHS1))
Épitope
Tous les épitopes à travers Nephrin Anticorps.
Middle Region
Reactivité
Toutes les réactivités sur Nephrin Anticorps
Humain
Hôte
Toutes les hôtes sur Nephrin Anticorps
Lapin
Clonalité
Toutes les clonalités sur Nephrin Anticorps
Polyclonal
Conjugué
Tous les conjugués à travers Nephrin Anticorps
Cet anticorp Nephrin est non-conjugé
Application
Tous les applications à travers Nephrin Anticorps.
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
Purification
Affinity chromatography purified via peptide column
Immunogène
16 amino acid synthetic peptide from near the center of human Nephrin
Isotype
IgG
Top Product
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Alternatives
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Information d'application
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Indications d'application
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Stockage
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Concentration
1.0 mg/mL
Buffer
PBS containing 0.02 % Sodium azide as preservative
Agent conservateur
Sodium azide
Précaution d'utilisation
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Conseil sur la manipulation
Avoid repeated freezing and thawing.
Stock
4 °C/-20 °C
Stockage commentaire
Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Détails sur Nephrin
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Antigène
Nephrin (NPHS1)
(Nephrosis 1, Congenital, Finnish Type (Nephrin) (NPHS1))
Autre désignation
Nephrin (NPHS1 Produits )
Synonymes
anticorps NPHS1, anticorps nphs1l, anticorps nphs1, anticorps CNF, anticorps NPHN, anticorps nephrin, anticorps NephrinB, anticorps NPHS1, nephrin, anticorps nephrosis 1, congenital, Finnish type (nephrin), anticorps NPHS1 nephrin S homeolog, anticorps nephrin, anticorps NPHS1 nephrin, anticorps nephrosis 1, nephrin, anticorps NPHS1, anticorps nphs1, anticorps nphs1.S, anticorps LOC5579127, anticorps Nphs1
Sujet
Nephrin is strongly expressed in renal glomeruli and is a member of the immunoglobulin family of cell adhesion molecules. Mutations in the Nephrin gene result in congenital nephrotic syndrome, an autosomal-recessive disorder characterized by massive proteinuria in utero and nephrosis at birth. Renal glomeruli allow normal kidneys to filter plasma so that it is very pure. Nephrin is expressed in the podocyte slit-diaphragm of the renal glomeruli in a manner that suggests that Nephrin molecules homodimerize in an anti-parallel fashion similar to cadherin interactions in adherens junctions. Thus, Nephrin may constitute the entire extracellular structure of the slit-diaphragm.Synonyms: NPHN, NPHS1
ID gène
4868
NCBI Accession
NP_004637
Pathways
Regulation of Actin Filament Polymerization , Skeletal Muscle Fiber Development
Vus récemment
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