PARP1 anticorps (AA 150-250)

N° du produit ABIN1513308

Cet anticorps anti-PARP1 est un anticorps Lapin Polyclonal détectant PARP1 dans WB et IHC. Adapté pour Humain.

Aperçu rapide pour PARP1 anticorps (AA 150-250) (ABIN1513308)

Antigène: PARP1 (Poly (ADP-Ribose) Polymerase 1 (PARP1))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PARP1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Détail du produit anti-PARP1 anticorps

Épitope: AA 150-250

Séquence: QLGMIDRWYH PGCFVKNREE LGFRPEYSAS QLKGFSLLAT EDKEALKKQL PGVKSEGKRK GDEVDGVDEV AKKKSKKEKD KDSKLEKALK AQNDLIWNIK D

Réactivité croisée: Humain, Souris, Rat

Attributs du produit: Polyclonal Antibodies

Purification: Affinity purification

Immunogène: A synthetic peptide corresponding to a sequence within amino acids 150-250 of human PARP1 (NP_001609.2).

Isotype: IgG

Information d'application

Indications d'application: WB,1:1000 - 1:2000,IHC,1:50 - 1:200

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid freeze / thaw cycles

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur PARP1

Antigène: PARP1 (Poly (ADP-Ribose) Polymerase 1 (PARP1))

Autre désignation: PARP1

Sujet: This gene encodes a chromatin-associated enzyme, poly(ADP-ribosyl)transferase, which modifies various nuclear proteins by poly(ADP-ribosyl)ation. The modification is dependent on DNA and is involved in the regulation of various important cellular processes such as differentiation, proliferation, and tumor transformation and also in the regulation of the molecular events involved in the recovery of cell from DNA damage. In addition, this enzyme may be the site of mutation in Fanconi anemia, and may participate in the pathophysiology of type I diabetes.,ADPRT,ADPRT 1,ADPRT1,ARTD1,PARP,PARP-1,PPOL,pADPRT-1,PARP1,Cleaved PARP,PARP1,Epigenetics & Nuclear Signaling,Chromatin Modifying Enzymes,other,DNA Damage & Repair,RNA Binding,Signal Transduction,Cell Biology & Developmental Biology,Cell Cycle,Centrosome,Death Receptor Signaling Pathway,Immunology & Inflammation,NF-kB Signaling Pathway,PARP1

Poids moléculaire: 113 kDa

ID gène: 142

UniProt: P09874

Pathways: Apoptose, Caspase Cascade in Apoptosis, Réparation de l'ADN, Production of Molecular Mediator of Immune Response, Maintenance of Protein Location