SHP1 anticorps (pTyr536)

N° du produit ABIN1531195

L’anticorps Lapin Polyclonal anti-SHP1 a été validé pour WB, ELISA et IHC. Il convient pour détecter SHP1 dans des échantillons de Humain, Souris et Rat.

Aperçu rapide pour SHP1 anticorps (pTyr536) (ABIN1531195)

Antigène: SHP1 (PTPN6) (Protein-tyrosine Phosphatase 1C (PTPN6))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SHP1 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Détail du produit anti-SHP1 anticorps

Épitope: AA 502-551, pTyr536

Specificité:

SHP-1 (Phospho-Tyr536) Antibody detects endogenous levels of SHP-1 only when phosphorylated at Tyr536.

PhosphorylationH:Y536 M:Y536 R:Y538

Purification: The antibody was purified from rabbit antiserum by affinity-chromatography using phospho peptide. The antibody against non-phospho peptide was removed by chromatography using corresponding non-phospho peptide.

Pureté: > 95 %

Immunogène: The antiserum was produced against synthesized peptide derived from human SHP-1 around the phosphorylation site of Tyr536.

Isotype: IgG

Information d'application

Indications d'application: WB: 1:500~1:1000 IHC: 1:50~1:100 ELISA: 1:10000

Commentaires:

Unigene-Number: Hs.63489 (NCBI Gene Symbol: PTPN6)

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Stable at -20°C for at least 1 year.

Date de péremption: 12 months

Détails sur SHP1

Antigène: SHP1 (PTPN6) (Protein-tyrosine Phosphatase 1C (PTPN6))

Autre désignation: SHP-1

Sujet:

Synonyms: 70Z-SHP, HCP, HCPH, Hematopoietic cell protein-tyrosine phosphatase, PTN6, PTP-1C, PTP1C, PTPN6, Protein-tyrosine phosphatase 1C, Protein-tyrosine phosphatase SHP-1, Protein-tyrosine phosphatase, non-receptor type 6, SH-PTP1

NCBI Gene Symbol: PTPN6

Poids moléculaire: 67 kDa

ID gène: 5777

OMIM: 176883

UniProt: P29350

Pathways: Signalistation JAK/STAT, TCR Signaling, Signalisation TLR, Nuclear Receptor Transcription Pathway, Positive Regulation of Peptide Hormone Secretion, Steroid Hormone Mediated Signaling Pathway, Response to Growth Hormone Stimulus, Regulation of Leukocyte Mediated Immunity, CXCR4-mediated Signaling Events, Signaling Events mediated by VEGFR1 and VEGFR2, BCR Signaling