Src anticorps (pTyr419)
Aperçu rapide pour Src anticorps (pTyr419) (ABIN1531971)
Antigène
Voir toutes Src AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 386-435, pTyr419
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Specificité
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Src (Phospho-Tyr418) Antibody detects endogenous levels of Src only when phosphorylated at Tyr418.
PhosphorylationH:Y419 M:Y424 R:Y419
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Purification
- The antibody was purified from rabbit antiserum by affinity-chromatography using phospho peptide. The antibody against non-phospho peptide was removed by chromatography using corresponding non-phospho peptide.
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Pureté
- > 95 %
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Immunogène
- The antiserum was produced against synthesized peptide derived from human Src around the phosphorylation site of Tyr418.
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Isotype
- IgG
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Indications d'application
- WB: 1:500~1:1000 IHC: 1:50~1:100 ELISA: 1:20000
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Commentaires
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Unigene-Number: Hs.195659 (NCBI Gene Symbol: SRC)
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Stable at -20°C for at least 1 year.
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Date de péremption
- 12 months
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- Src (Proto-oncogene tyrosine-protein kinase Src (Src))
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Autre désignation
- Src
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Sujet
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Synonyms: c-Src, C-SRC, kinase Src, Neuronal SRC, p60-SRC, p60-Src, Src, SRC, SRC1
NCBI Gene Symbol: SRC
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Poids moléculaire
- 59 kDa
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ID gène
- 6714
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OMIM
- 190090
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UniProt
- P12931
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Pathways
- Signalistation JAK/STAT, Neurotrophin Signaling Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, Cellular Response to Molecule of Bacterial Origin, Cell-Cell Junction Organization, Regulation of Carbohydrate Metabolic Process, Autophagy, CXCR4-mediated Signaling Events, Signaling Events mediated by VEGFR1 and VEGFR2, Smooth Muscle Cell Migration, Negative Regulation of intrinsic apoptotic Signaling, Platelet-derived growth Factor Receptor Signaling, Thromboxane A2 Receptor Signaling, Signaling of Hepatocyte Growth Factor Receptor, VEGF Signaling
Antigène
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