FRS2 anticorps (pTyr436)

N° du produit ABIN1532103

Détail du produit anti-FRS2 anticorps

Antigène: FRS2 (Fibroblast Growth Factor Receptor Substrate 2 (FRS2))

Épitope: AA 402-451, pTyr436

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp FRS2 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Specificité:

FRS2 (Phospho-Tyr436) Antibody detects endogenous levels of FRS2 only when phosphorylated at Tyr436.

PhosphorylationH:Y436 M:Y436

Purification: The antibody was purified from rabbit antiserum by affinity-chromatography using phospho peptide. The antibody against non-phospho peptide was removed by chromatography using corresponding non-phospho peptide.

Pureté: > 95 %

Immunogène: The antiserum was produced against synthesized peptide derived from human FRS2 around the phosphorylation site of Tyr436.

Isotype: IgG

Information d'application

Indications d'application: WB: 1:500~1:1000 IHC: 1:50~1:100 ELISA: 1:10000

Commentaires:

Unigene-Number: Hs.593446 (NCBI Gene Symbol: FRS2)

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Stable at -20°C for at least 1 year.

Date de péremption: 12 months

Références pour anticorps anti-FRS2 (ABIN1532103)

Sun, Zou, Yang, Morita, Gong, Shiba, Akagawa, Yuan: "Inorganic polyphosphates stimulate FGF23 expression through the FGFR pathway." dans: Biochemical and biophysical research communications, Vol. 428, Issue 2, pp. 298-302, (2012) (PubMed).

Détails sur FRS2

Antigène: FRS2 (Fibroblast Growth Factor Receptor Substrate 2 (FRS2))

Autre désignation: FRS2 (FRS2 Produits)

Synonymes: anticorps frs2, anticorps wu:fd21h10, anticorps zgc:91973, anticorps FRS2A, anticorps FRS2alpha, anticorps SNT, anticorps SNT-1, anticorps SNT1, anticorps 4732458E18, anticorps C330018A15Rik, anticorps Frs2alpha, anticorps fibroblast growth factor receptor substrate 2, anticorps fibroblast growth factor receptor substrate 2b, anticorps FRS2, anticorps frs2b, anticorps Frs2

Sujet:

Synonyms: FGFR signalling adaptor, FGFR signalling adaptor SNT-1, SNT-1, SNT2, SUC1-associated neurotrophic factor target, Suc1-associated neurotrophic factor target

NCBI Gene Symbol: FRS2

Poids moléculaire: 57 kDa

ID gène: 10818

OMIM: 607743

UniProt: Q8WU20

Pathways: Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Signaling Events mediated by VEGFR1 and VEGFR2