Insulin anticorps (AA 35-64)

N° du produit ABIN1539839

L’anticorps Souris Monoclonal anti-Insulin a été validé pour WB. Il convient pour détecter Insulin dans des échantillons de Humain.

Aperçu rapide pour Insulin anticorps (AA 35-64) (ABIN1539839)

Antigène: Insulin (INS)

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp Insulin est non-conjugé

Application: Western Blotting (WB)

Clone: 396CT20-4-4

Détail du produit anti-Insulin anticorps

Épitope: AA 35-64

Purification: Mouse monoclonal antibody supplied in crude ascites with 0.09% (W/V) sodium azide.

Immunogène: This INS antibody is generated from mice immunized with a KLH conjugated synthetic peptide between 35-64 amino acids from human INS.

Isotype: IgM

Information d'application

Indications d'application: WB: 1:1000~8000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Mouse monoclonal antibody supplied in crude ascites with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: INS Antibody (Ascites) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, keep at -20 °C.

Date de péremption: 6 months

Détails sur Insulin

Antigène: Insulin (INS)

Autre désignation: INS

Sujet: After removal of the precursor signal peptide, proinsulin is post-translationally cleaved into three peptides: the B chain and A chain peptides, which are covalently linked via two disulfide bonds to form insulin, and C-peptide. Binding of insulin to the insulin receptor (INSR) stimulates glucose uptake. A multitude of mutant alleles with phenotypic effects have been identified. There is a read-through gene, INS-IGF2, which overlaps with this gene at the 5' region and with the IGF2 gene at the 3' region. Alternative splicing results in multiple transcript variants. [provided by RefSeq].

Poids moléculaire: 11981

ID gène: 3630

NCBI Accession: NP_000198, NP_001172026, NP_001172027

UniProt: P01308

Pathways: Signalisation NF-kappaB, Signalisation RTK, Positive Regulation of Peptide Hormone Secretion, Peptide Hormone Metabolism, Hormone Activity, Carbohydrate Homeostasis, ER-Nucleus Signaling, Regulation of Carbohydrate Metabolic Process, Feeding Behaviour, Autophagy, Negative Regulation of intrinsic apoptotic Signaling, Brown Fat Cell Differentiation, Positive Regulation of fat Cell Differentiation