DDX60 anticorps
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- Antigène Voir toutes DDX60 Anticorps
- DDX60 (DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 60 (DDX60))
- Reactivité
- Humain, Souris, Rat
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp DDX60 est non-conjugé
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Application
- Western Blotting (WB), ELISA, Immunofluorescence (IF)
- Specificité
- At least three isoforms of DDX60 are known to exist, this antibody will detect all three isoforms.
- Purification
- Affinity chromatography purified via peptide column
- Immunogène
- DDX60 antibody was raised against a 17 amino acid synthetic peptide near the center of human DDX60.
- Isotype
- IgG
- Top Product
- Discover our top product DDX60 Anticorps primaire
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- Indications d'application
- DDX60 antibody can be used for detection of DDX60 by Western blot at 1 - 2 μg/mL. For immunofluorescence start at 20 μg/mL.
- Commentaires
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(IN) DEAD box protein 60
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- PBS containing 0.02 % Sodium azide.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
- Stock
- 4 °C
- Stockage commentaire
- DDX60 antibody can be stored at 4 °C for three months. At -20 °C stable for up to one year.
- Date de péremption
- 12 months
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- Antigène
- DDX60 (DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 60 (DDX60))
- Autre désignation
- DDX60 (DDX60 Produits)
- Synonymes
- anticorps 9830118M07, anticorps RGD1560014, anticorps DExD/H-box helicase 60, anticorps DEAD (Asp-Glu-Ala-Asp) box polypeptide 60, anticorps DEXD/H-box helicase 60, anticorps DDX60, anticorps Ddx60
- Sujet
- DDX60 is a DEXD/H Box RNA helicase and the human homolog of the S. cerevisiae Ski2, a cofactor of RNA exosome. Expression of DDX60 increases after viral infection and binds to endogenous RIG-I, a cytoplasmic viral RNA sensor, as well as other RIG-I-like receptors such as MDA5 and LGP2. These proteins activate TBK1 and IKK-e, signaling IRF3 and NF-kB-responsive genes in the innate immune response pathway. DDX60 is required for the RIG-I- or MDA5-dependent response to viral infection, but is dispensable for TLR3-mediated signaling.
- Poids moléculaire
- 188 kDa
- ID gène
- 55601
- NCBI Accession
- NP_060101
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