CYP24A1 anticorps (AA 36-448)

N° du produit ABIN1679472

Détail du produit anti-CYP24A1 anticorps

Antigène: CYP24A1 (Cytochrome P450, Family 24, Subfamily A, Polypeptide 1 (CYP24A1))

Épitope: AA 36-448

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CYP24A1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Séquence: PQPREVPVCP LTAGGETQNA AALPGPTSWP LLGSLLQILW KGGLKKQHDT LVEYHKKYGK IFRMKLGSFE SVHLGSPCLL EALYRTESAY PQRLEIKPWK AYRDYRKEGY GLLILEGEDW QRVRSAFQKK LMKPGEVMKL DNKINEVLAD FMGRIDELCD ERGHVEDLYS ELNKWSFESI CLVLYEKRFG LLQKNAGDEA VNFIMAIKTM MSTFGRMMVT PVELHKSLNT KVWQDHTLAW DTIFKSVKAC IDNRLEKYSQ QPSADFLCDI YHQNRLSKKE LYAAVTELQL AAVETTANSL MWILYNLSRN PQVQQKLLKE IQSVLPENQV PRAEDLRNMP YLKACLKESM RLTPSVPFTT RTLDKATVLG EYALPKGIVR KYDIQATDNE PVEMLHSGTL VPSRELPIAF CQR

Réactivité croisée: Humain, Souris, Rat

Attributs du produit: Polyclonal Antibodies

Purification: Affinity purification

Immunogène: Recombinant fusion protein containing a sequence corresponding to amino acids 36-448 of human CYP24A1 (NP_001122387.1).

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:2000,IHC,1:50 - 1:100

Restrictions: For Research Use only

Stockage

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur CYP24A1

Antigène: CYP24A1 (Cytochrome P450, Family 24, Subfamily A, Polypeptide 1 (CYP24A1))

Autre désignation: CYP24A1 (CYP24A1 Produits)

Synonymes: anticorps CP24, anticorps CYP24, anticorps HCAI, anticorps P450-CC24, anticorps 24-OHase, anticorps Cyp24, anticorps 25-hydroxyvitaminD324-hydroxylase, anticorps VITD12, anticorps CP450CC24, anticorps cytochrome P450 family 24 subfamily A member 1, anticorps cytochrome P450, family 24, subfamily a, polypeptide 1, anticorps cytochrome P450, family 24, subfamily A, polypeptide 1, anticorps CYP24A1, anticorps Cyp24a1

Sujet: This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This mitochondrial protein initiates the degradation of 1,25-dihydroxyvitamin D3, the physiologically active form of vitamin D3, by hydroxylation of the side chain. In regulating the level of vitamin D3, this enzyme plays a role in calcium homeostasis and the vitamin D endocrine system. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.,CYP24A1,CP24,CYP24,HCAI,HCINF1,P450-CC24,Cancer,Signal Transduction,Endocrine & Metabolism,Mitochondrial metabolism,Cytochromes,Mitochondrial markers,Lipid Metabolism,Cytochromes,Lipases,Cardiovascular,Lipids,CYP24A1

Poids moléculaire: 43 kDa/51 kDa/58 kDa

ID gène: 1591

UniProt: Q07973

Pathways: Metabolism of Steroid Hormones and Vitamin D