Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
Purification
This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Immunogène
This CYP24A1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 466-494 amino acids from the C-terminal region of human CYP24A1.
anticorps CP24, anticorps CYP24, anticorps HCAI, anticorps P450-CC24, anticorps 24-OHase, anticorps Cyp24, anticorps 25-hydroxyvitaminD324-hydroxylase, anticorps VITD12, anticorps CP450CC24, anticorps cytochrome P450 family 24 subfamily A member 1, anticorps cytochrome P450, family 24, subfamily a, polypeptide 1, anticorps cytochrome P450, family 24, subfamily A, polypeptide 1, anticorps CYP24A1, anticorps Cyp24a1
Sujet
CYP24A1 is a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This mitochondrial protein initiates the degradation of 1,25-dihydroxyvitamin D3, the physiologically active form of vitamin D3, by hydroxylation of the side chain. In regulating the level of vitamin D3, this enzyme plays a role in calcium homeostasis and the vitamin D endocrine system.