CREB1 anticorps (Ser133)

N° du produit ABIN1685160

Détail du produit anti-CREB1 anticorps

Antigène: CREB1 (cAMP Responsive Element Binding Protein 1 (CREB1))

Épitope: Ser133

Reactivité: Humain, Souris, Rat

Hôte: Souris

Clonalité: Polyclonal

Conjugué: Cet anticorp CREB1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Purification: Purified

Stérilité: Sterile filtered

Immunogène: Polyclonal p-CREB-1 antibody was produced from sera of mice immunized with synthetic protein containing residues surrounding ser133 .

Isotype: IgG

Information d'application

Indications d'application: ELISA: Use at a concentration range of 1-2 µg/mL.
Western blot: A suitable range of concentrations of this antibody for WB detection is 10 µg/mL. WB analysis mouse hippocampal tissue lysate expressing phospho CREB1. ABIN1685160 was used as primary antibody.
IHC: A suitable range of concentrations of this antibody for IHC is 10 µg/mL. Immunohistochemical analysis of frozen mouse hyppocampal sections expressing CREB1. ABIN1685160 was used as primary antibody, dilution 1:200. Immunohistochemical analysis of FFPE mouse thymocytes expressing phospho CREB-1. ABIN1685160 was used as primary antibody, dilution 1:500.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: A quick spin of the vial followed by reconstitution in distilled water. This solution can then be diluted into other buffers

Buffer: PBS solution at a concentration of 1 mg/mL.

Conseil sur la manipulation: Avoid repeated freeze/thaw cycles.

Stock: -20 °C

Stockage commentaire: Recombinant IL-21R, as supplied, can be stored in working aliquots at - 8 °C for one month, or at -20 °C to -70 °C for twelve months.

Date de péremption: 12 months

Détails sur CREB1

Antigène: CREB1 (cAMP Responsive Element Binding Protein 1 (CREB1))

Autre désignation: CREB1 (CREB1 Produits)

Synonymes: anticorps creb, anticorps CREB1, anticorps Creb1, anticorps CREB, anticorps 2310001E10Rik, anticorps 3526402H21Rik, anticorps AV083133, anticorps Creb, anticorps Creb-1, anticorps creb1, anticorps zgc:55598, anticorps cAMP responsive element binding protein 1, anticorps cAMP responsive element binding protein, anticorps cAMP responsive element binding protein 1 S homeolog, anticorps cAMP responsive element binding protein 1a, anticorps CREB1, anticorps creb1, anticorps CREB, anticorps Creb1, anticorps creb1.S, anticorps creb1a

Sujet: The IL-21 receptor (IL-21R) is structurally related to IL-2R and IL-15R. In addition, these receptors, together with IL-4R, IL-7R, and IL-9R, share a common gamma -chain. IL-21R appears in T, natural killer (NK), B, and dendritic cells (DC), and it plays an important role in the regulation and function of these cells. IL-21 has, however, an effect on NK cells depending on their activation state. It enhances the proliferation and cytotoxic activity of activated NK cells, but in these cells, IL-21 also promotes apoptosis and thus limits NK cell response. In contrast, IL-21 inhibits IL-15-induced proliferation and maturation of NK cell precursors

UniProt: P16220

Pathways: Signalisation TLR, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Thyroid Hormone Synthesis, Activation of Innate immune Response, Myometrial Relaxation and Contraction, Regulation of Cell Size, Toll-Like Receptors Cascades, G-protein mediated Events, Interaction of EGFR with phospholipase C-gamma, Positive Regulation of fat Cell Differentiation