ZFAND5 anticorps (AA 121-213) (Biotin)

N° du produit ABIN1700823

Détail du produit anti-ZFAND5 anticorps (Biotin)

Antigène: ZFAND5 (Zinc Finger, AN1-Type Domain 5 (ZFAND5))

Épitope: AA 121-213

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ZFAND5 est conjugé à/à la Biotin

Application: ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Homologie: Human,Mouse,Rat,Cow,Sheep,Pig,Chicken,Rabbit

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human ZFAND5

Isotype: IgG

Information d'application

Indications d'application: IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C for 12 months.

Date de péremption: 12 months

Détails sur ZFAND5

Antigène: ZFAND5 (Zinc Finger, AN1-Type Domain 5 (ZFAND5))

Autre désignation: ZFAND5 (ZFAND5 Produits)

Synonymes: anticorps 2310057A04Rik, anticorps 5830475F03Rik, anticorps AA415485, anticorps Za20d2, anticorps Zfp216, anticorps ZA20D2, anticorps ZFAND5A, anticorps ZNF216, anticorps wu:fi29f06, anticorps za20d2l, anticorps zgc:56057, anticorps za20d2, anticorps zfand5, anticorps zfand5-a, anticorps zfand5-b, anticorps zfand5a, anticorps znf216, anticorps id:ibd2892, anticorps wu:fb16d02, anticorps wu:fc67h07, anticorps zgc:73363, anticorps zinc finger, AN1-type domain 5, anticorps zinc finger AN1-type containing 5, anticorps zinc finger, AN1-type domain 5b, anticorps zinc finger AN1-type containing 5 L homeolog, anticorps zinc finger, AN1-type domain 5a, anticorps Zfand5, anticorps ZFAND5, anticorps zfand5b, anticorps zfand5.L, anticorps zfand5a

Sujet:

Synonyms: ZA20D2, ZNF216, ZFAND5A, AN1-type zinc finger protein 5, Zinc finger A20 domain-containing protein 2, Zinc finger protein 216, ZFAND5

Background: Involved in protein degradation via the ubiquitin-proteasome system. May act by anchoring ubiquitinated proteins to the proteasome. Plays a role in ubiquitin-mediated protein degradation during muscle atrophy. Plays a role in the regulation of NF-kappa-B activation and apoptosis. Inhibits NF-kappa-B activation triggered by overexpression of RIPK1 and TRAF6 but not of RELA. Inhibits also tumor necrosis factor (TNF), IL-1 and TLR4-induced NF-kappa-B activation in a dose-dependent manner. Overexpression sensitizes cells to TNF-induced apoptosis. Is a potent inhibitory factor for osteoclast differentiation.

ID gène: 7763

UniProt: O76080

Pathways: Platelet-derived growth Factor Receptor Signaling