ZFAND5 anticorps

N° du produit ABIN7245737

Détail du produit anti-ZFAND5 anticorps

Antigène: ZFAND5 (Zinc Finger, AN1-Type Domain 5 (ZFAND5))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ZFAND5 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Attributs du produit: Polyclonal Antibody

Purification: Antigen affinity purification

Immunogène: Full length fusion protein

Isotype: IgG

Information d'application

Indications d'application: WB 1:500-1:2000, IHC 1:25-1:100, ELISA 1:5000-1:10000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1.4 mg/mL

Buffer: PBS with 0.05 % Sodium azide and 40 % Glycerol, pH 7.4

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur ZFAND5

Antigène: ZFAND5 (Zinc Finger, AN1-Type Domain 5 (ZFAND5))

Autre désignation: ZFAND5 (ZFAND5 Produits)

Synonymes: anticorps 2310057A04Rik, anticorps 5830475F03Rik, anticorps AA415485, anticorps Za20d2, anticorps Zfp216, anticorps ZA20D2, anticorps ZFAND5A, anticorps ZNF216, anticorps wu:fi29f06, anticorps za20d2l, anticorps zgc:56057, anticorps za20d2, anticorps zfand5, anticorps zfand5-a, anticorps zfand5-b, anticorps zfand5a, anticorps znf216, anticorps id:ibd2892, anticorps wu:fb16d02, anticorps wu:fc67h07, anticorps zgc:73363, anticorps zinc finger, AN1-type domain 5, anticorps zinc finger AN1-type containing 5, anticorps zinc finger, AN1-type domain 5b, anticorps zinc finger AN1-type containing 5 L homeolog, anticorps zinc finger, AN1-type domain 5a, anticorps Zfand5, anticorps ZFAND5, anticorps zfand5b, anticorps zfand5.L, anticorps zfand5a

Sujet: Involved in protein degradation via the ubiquitin-proteasome system. May act by anchoring ubiquitinated proteins to the proteasome. Plays a role in ubiquitin-mediated protein degradation during muscle atrophy. Plays a role in the regulation of NF-kappa-B activation and apoptosis. Inhibits NF-kappa-B activation triggered by overexpression of RIPK1 and TRAF6 but not of RELA. Inhibits also tumor necrosis factor (TNF), IL-1 and TLR4-induced NF-kappa-B activation in a dose-dependent manner. Overexpression sensitizes cells to TNF-induced apoptosis. Is a potent inhibitory factor for osteoclast differentiation.

Poids moléculaire:

Observed_MW: Refer to figures

Calculated_MW: 23 kDa

UniProt: O76080

Pathways: Platelet-derived growth Factor Receptor Signaling