ZFAND5 anticorps (AA 40-150)

N° du produit ABIN6150428

Détail du produit anti-ZFAND5 anticorps

Antigène: ZFAND5 (Zinc Finger, AN1-Type Domain 5 (ZFAND5))

Épitope: AA 40-150

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ZFAND5 est non-conjugé

Application: Western Blotting (WB)

Séquence: RQQNSGRMSP MGTASGSNSP TSDSASVQRA DTSLNNCEGA AGSTSEKSRN VPVAALPVTQ QMTEMSISRE DKITTPKTEV SEPVVTQPSP SVSQPSTSQS EEKAPELPKP K

Réactivité croisée: Souris

Attributs du produit: Polyclonal Antibodies

Immunogène: Recombinant fusion protein containing a sequence corresponding to amino acids 40-150 of human ZFAND5 (NP_001095890.1).

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur ZFAND5

Antigène: ZFAND5 (Zinc Finger, AN1-Type Domain 5 (ZFAND5))

Autre désignation: ZFAND5 (ZFAND5 Produits)

Synonymes: anticorps 2310057A04Rik, anticorps 5830475F03Rik, anticorps AA415485, anticorps Za20d2, anticorps Zfp216, anticorps ZA20D2, anticorps ZFAND5A, anticorps ZNF216, anticorps wu:fi29f06, anticorps za20d2l, anticorps zgc:56057, anticorps za20d2, anticorps zfand5, anticorps zfand5-a, anticorps zfand5-b, anticorps zfand5a, anticorps znf216, anticorps id:ibd2892, anticorps wu:fb16d02, anticorps wu:fc67h07, anticorps zgc:73363, anticorps zinc finger, AN1-type domain 5, anticorps zinc finger AN1-type containing 5, anticorps zinc finger, AN1-type domain 5b, anticorps zinc finger AN1-type containing 5 L homeolog, anticorps zinc finger, AN1-type domain 5a, anticorps Zfand5, anticorps ZFAND5, anticorps zfand5b, anticorps zfand5.L, anticorps zfand5a

Sujet: Involved in protein degradation via the ubiquitin-proteasome system. May act by anchoring ubiquitinated proteins to the proteasome. Plays a role in ubiquitin-mediated protein degradation during muscle atrophy. Plays a role in the regulation of NF-kappa-B activation and apoptosis. Inhibits NF-kappa-B activation triggered by overexpression of RIPK1 and TRAF6 but not of RELA. Inhibits also tumor necrosis factor (TNF, IL-1 and TLR4-induced NF-kappa-B activation in a dose-dependent manner. Overexpression sensitizes cells to TNF-induced apoptosis. Is a potent inhibitory factor for osteoclast differentiation.,ZFAND5,ZA20D2,ZFAND5A,ZNF216,Epigenetics & Nuclear Signaling,Signal Transduction,Cell Biology & Developmental Biology,Apoptosis,Cytoskeleton,Extracellular Matrix,Bone,ZFAND5

Poids moléculaire: 23 kDa

ID gène: 7763

UniProt: O76080

Pathways: Platelet-derived growth Factor Receptor Signaling