PIK3 gamma anticorps (pSer1101) (Cy5)

N° du produit ABIN1704380

L’anticorps Lapin Polyclonal anti-PIK3 gamma a été validé pour WB, IF (cc) et IF (p). Il convient pour détecter PIK3 gamma dans des échantillons de Humain.

Aperçu rapide pour PIK3 gamma anticorps (pSer1101) (Cy5) (ABIN1704380)

Antigène: PIK3 gamma (PIK3CG) (Phosphoinositide-3-Kinase, Catalytic, gamma Polypeptide (PIK3CG))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PIK3 gamma est conjugé à/à la Cy5

Application: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Détail du produit anti-PIK3 gamma anticorps (Cy5)

Épitope: pSer1101

Homologie: Human,Mouse,Rat,Dog,Cow,Sheep,Pig,Horse,Chicken,Rabbit

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic phosphopeptide derived from human PIK3 gamma around the phosphorylation site of Ser1101

Isotype: IgG

Information d'application

Indications d'application: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Date de péremption: 12 months

Détails sur PIK3 gamma

Antigène: PIK3 gamma (PIK3CG) (Phosphoinositide-3-Kinase, Catalytic, gamma Polypeptide (PIK3CG))

Sujet:

Synonyms: PK3CG_HUMAN, Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform, PI3-kinase subunit gamma, PI3K-gamma, PI3Kgamma, PtdIns-3-kinase subunit gamma, Phosphatidylinositol 4,5-bisphosphate 3-kinase 110 kDa catalytic subunit gamma, PtdIns-3-kinase subunit p110-gamma, p110gamma, Phosphoinositide-3-kinase catalytic gamma polypeptide, Serine/threonine protein kinase PIK3CG, 1 phosphatidylinositol 3 kinase, p120-PI3K, p120 PI3K, 5-bisphosphate 3-kinase 110 kDa catalytic subunit gamma, 5-bisphosphate 3-kinase catalytic subunit gamma isoform, p110 gamma, Phosphatidylinositol 3 kinase catalytic 110 kD gamma,

Background: This gene encodes a protein that belongs to the pi3/pi4-kinase family of proteins. The gene product is an enzyme that phosphorylates phosphoinositides on the 3-hydroxyl group of the inositol ring. It is an important modulator of extracellular signals, including those elicited by E-cadherin-mediated cell-cell adhesion, which plays an important role in maintenance of the structural and functional integrity of epithelia. In addition to its role in promoting assembly of adherens junctions, the protein is thought to play a pivotal role in the regulation of cytotoxicity in NK cells. The gene is located in a commonly deleted segment of chromosome 7 previously identified in myeloid leukemias. [provided by RefSeq, Jul 2008].

ID gène: 5294

Pathways: Signalisation PI3K-Akt, Signalisation RTK, AMPK Signaling, Signalisation TLR, Inositol Metabolic Process, Hepatitis C, VEGF Signaling