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PAG1 anticorps (AA 331-432)

PAG1 Reactivité: Souris, Rat WB, ELISA, IHC (p), FACS, IF (cc), IF (p), ICC, IHC (fro) Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN1713878
  • Antigène Voir toutes PAG1 Anticorps
    PAG1 (phosphoprotein Associated with Glycosphingolipid Microdomains 1 (PAG1))
    Épitope
    • 15
    • 10
    • 4
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 331-432
    Reactivité
    • 27
    • 26
    • 24
    • 12
    • 1
    • 1
    • 1
    • 1
    • 1
    Souris, Rat
    Hôte
    • 42
    • 4
    Lapin
    Clonalité
    • 42
    • 4
    Polyclonal
    Conjugué
    • 18
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp PAG1 est non-conjugé
    Application
    • 20
    • 15
    • 12
    • 12
    • 9
    • 7
    • 6
    • 5
    • 5
    • 2
    • 2
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunocytochemistry (ICC), Immunohistochemistry (Frozen Sections) (IHC (fro))
    Homologie
    Human,Dog,Horse,Rabbit
    Purification
    Purified by Protein A.
    Immunogène
    KLH conjugated synthetic peptide derived from human PAG1
    Isotype
    IgG
  • Indications d'application
    WB 1:300-5000
    ELISA 1:500-1000
    FCM 1:20-100
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    ICC 1:100-500
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    0.01M TBS( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Agent conservateur
    ProClin
    Précaution d'utilisation
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    Date de péremption
    12 months
  • Antigène
    PAG1 (phosphoprotein Associated with Glycosphingolipid Microdomains 1 (PAG1))
    Autre désignation
    PAG1 (PAG1 Produits)
    Synonymes
    anticorps Cbp, anticorps F730007C19Rik, anticorps Pag, anticorps CBP, anticorps PAG, anticorps MGC80192, anticorps phosphoprotein associated with glycosphingolipid microdomains 1, anticorps phosphoprotein membrane anchor with glycosphingolipid microdomains 1, anticorps phosphoprotein membrane anchor with glycosphingolipid microdomains 1 L homeolog, anticorps Pag1, anticorps PAG1, anticorps pag1.L, anticorps pag1
    Sujet

    Negatively regulates TCR (T-cell antigen receptor)-mediated signaling in T-cells and FCER1 (high affinity immunoglobulin epsilon receptor)-mediated signaling in mast cells. Promotes CSK activation and recruitment to lipid rafts, which results in LCK inhibition. Inhibits immunological synapse formation by preventing dynamic arrangement of lipid raft proteins. May be involved in cell adhesion signaling.

    Subcellular location: Cell membrane

    Synonyms: CBP, PAG, Phosphoprotein associated with glycosphingolipid-enriched microdomains 1, Csk-binding protein, Transmembrane adapter protein PAG, Transmembrane phosphoprotein Cbp, PAG1

    ID gène
    55824
    UniProt
    Q9NWQ8
    Pathways
    Signalisation p53, TCR Signaling, EGFR Signaling Pathway, CXCR4-mediated Signaling Events
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