PTP4A2 anticorps (AA 58-162)

N° du produit ABIN1724901

Détail du produit anti-PTP4A2 anticorps

Antigène: PTP4A2 (Protein tyrosine Phosphatase Type IVA, Member 2 (PTP4A2))

Épitope: AA 58-162

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp PTP4A2 est non-conjugé

Application: ELISA, Western Blotting (WB)

Purification: purified

Immunogène: Purified recombinant fragment of human PTP4A2 (AA: 58-162) expressed in E. coli.

Clone: 5B6F4

Isotype: IgG2b

Information d'application

Indications d'application: ELISA: 1:10000, WB: 1:500 - 1:2000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C/-20 °C

Stockage commentaire: 4°C, -20°C for long term storage

Références pour anticorps anti-PTP4A2 (ABIN1724901)

Hardy, Wong, Muller, Park, Tremblay: "Overexpression of the protein tyrosine phosphatase PRL-2 correlates with breast tumor formation and progression." dans: Cancer research, Vol. 70, Issue 21, pp. 8959-67, (2010) (PubMed).

Akiyama, Dhavan, Yi: "PRL-2 increases Epo and IL-3 responses in hematopoietic cells." dans: Blood cells, molecules & diseases, Vol. 44, Issue 4, pp. 209-14, (2010) (PubMed).

Détails sur PTP4A2

Antigène: PTP4A2 (Protein tyrosine Phosphatase Type IVA, Member 2 (PTP4A2))

Autre désignation: PTP4A2 (PTP4A2 Produits)

Synonymes: anticorps wu:fc05f09, anticorps wu:fi84b06, anticorps zgc:101724, anticorps MGC53390, anticorps MGC80084, anticorps MGC132077, anticorps PTP4A2, anticorps ptp4a2, anticorps Prl-2, anticorps HH13, anticorps HH7-2, anticorps HU-PP-1, anticorps OV-1, anticorps PRL-2, anticorps PRL2, anticorps PTP4A, anticorps PTPCAAX2, anticorps ptp-IV1a, anticorps ptp-IV1b, anticorps protein tyrosine phosphatase type IVA, member 2b, anticorps protein tyrosine phosphatase 4a2, anticorps protein tyrosine phosphatase type IVA, member 2, anticorps protein tyrosine phosphatase type IVA, member 2 L homeolog, anticorps ptp4a2b, anticorps ptp4a2, anticorps PTP4A2, anticorps ptp4a2.L, anticorps Ptp4a2

Sujet:

Description: The protein encoded by this gene belongs to a small class of the protein tyrosine phosphatase (PTP) family. PTPs are cell signaling molecules that play regulatory roles in a variety of cellular processes. PTPs in this class contain a protein tyrosine phosphatase catalytic domain and a characteristic C-terminal prenylation motif. This PTP has been shown to primarily associate with plasmic and endosomal membrane through its C-terminal prenylation. This PTP was found to interact with the beta-subunit of Rab geranylgeranyltransferase II (beta GGT II), and thus may function as a regulator of GGT II activity. Overexpression of this gene in mammalian cells conferred a transformed phenotype, which suggested its role in tumorigenesis. Alternatively spliced transcript variants have been described. Related pseudogenes exist on chromosomes 11, 12 and 17. ,

Aliases: HH13, OV-1, PRL2, HH7-2, PRL-2, PTP4A, HU-PP-1, PTPCAAX2, ptp-IV1a, ptp-IV1b

Poids moléculaire: 19.1 kDa

ID gène: 8073

HGNC: 8073