PTP4A2
Reactivité: Humain
WB, IHC, ICC
Hôte: Lapin
Polyclonal
unconjugated
Indications d'application
Optimal dilution of the PTP4A2 antibody should be determined by the researcher.\. Western blot: 0.1-0.5 μg/mL,IHC (Paraffin): 0.5-1 μg/mL,FACS: 1-3 μg/10^6 cells
Restrictions
For Research Use only
Buffer
0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
Stock
-20 °C
Stockage commentaire
After reconstitution, the PTP4A2 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
Antigène
PTP4A2
(Protein tyrosine Phosphatase Type IVA, Member 2 (PTP4A2))
anticorps wu:fc05f09, anticorps wu:fi84b06, anticorps zgc:101724, anticorps MGC53390, anticorps MGC80084, anticorps MGC132077, anticorps PTP4A2, anticorps ptp4a2, anticorps Prl-2, anticorps HH13, anticorps HH7-2, anticorps HU-PP-1, anticorps OV-1, anticorps PRL-2, anticorps PRL2, anticorps PTP4A, anticorps PTPCAAX2, anticorps ptp-IV1a, anticorps ptp-IV1b, anticorps protein tyrosine phosphatase type IVA, member 2b, anticorps protein tyrosine phosphatase 4a2, anticorps protein tyrosine phosphatase type IVA, member 2, anticorps protein tyrosine phosphatase type IVA, member 2 L homeolog, anticorps ptp4a2b, anticorps ptp4a2, anticorps PTP4A2, anticorps ptp4a2.L, anticorps Ptp4a2
Sujet
Protein tyrosine phosphatase type IVA 2 is an enzyme that in humans is encoded by the PTP4A2 gene. The protein encoded by this gene belongs to a small class of the protein tyrosine phosphatase (PTP) family. PTPs are cell signaling molecules that play regulatory roles in a variety of cellular processes. PTPs in this class contain a protein tyrosine phosphatase catalytic domain and a characteristic C-terminal prenylation motif. This PTP has been shown to primarily associate with plasmic and endosomal membrane through its C-terminal prenylation. This PTP was found to interact with the beta-subunit of Rab geranylgeranyltransferase II (beta GGT II), and thus may function as a regulator of GGT II activity. Overexpression of this gene in mammalian cells conferred a transformed phenotype, which suggested its role in tumorigenesis. Alternatively spliced transcript variants have been described. Related pseudogenes exist on chromosomes 11, 12 and 17.