anticorps wu:fc05f09, anticorps wu:fi84b06, anticorps zgc:101724, anticorps MGC53390, anticorps MGC80084, anticorps MGC132077, anticorps PTP4A2, anticorps ptp4a2, anticorps Prl-2, anticorps HH13, anticorps HH7-2, anticorps HU-PP-1, anticorps OV-1, anticorps PRL-2, anticorps PRL2, anticorps PTP4A, anticorps PTPCAAX2, anticorps ptp-IV1a, anticorps ptp-IV1b, anticorps protein tyrosine phosphatase type IVA, member 2b, anticorps protein tyrosine phosphatase 4a2, anticorps protein tyrosine phosphatase type IVA, member 2, anticorps protein tyrosine phosphatase type IVA, member 2 L homeolog, anticorps ptp4a2b, anticorps ptp4a2, anticorps PTP4A2, anticorps ptp4a2.L, anticorps Ptp4a2
Sujet
The protein encoded by this gene belongs to a small class of the protein tyrosine phosphatase (PTP) family. PTPs are cell signaling molecules that play regulatory roles in a variety of cellular processes. PTPs in this class contain a protein tyrosine phosphatase catalytic domain and a characteristic C-terminal prenylation motif. This PTP has been shown to primarily associate with plasmic and endosomal membrane through its C-terminal prenylation. This PTP was found to interact with the beta-subunit of Rab geranylgeranyltransferase II (beta GGT II), and thus may function as a regulator of GGT II activity. Overexpression of this gene in mammalian cells conferred a transformed phenotype, which suggested its role in tumorigenesis. Alternatively spliced transcript variants have been described. Related pseudogenes exist on chromosomes 11, 12 and 17.,PTP4A2,HH13,HH7-2,HU-PP-1,OV-1,PRL-2,PRL2,PTP4A,PTPCAAX2,ptp-IV1a,ptp-IV1b,Cancer,Signal Transduction,Kinase,Cell Biology & Developmental Biology,Cell Cycle,PTP4A2