BCL10 anticorps (N-Term)

N° du produit ABIN1732247

L’anticorps anti-BCL10 Polyclonal Lapin est utilisé pour la détection de BCL10 dans des échantillons de Humain. Il a été validé pour WB, IF, ICC et IHC (p).

Aperçu rapide pour BCL10 anticorps (N-Term) (ABIN1732247)

Antigène: BCL10 (B-Cell CLL/lymphoma 10 (BCL10))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp BCL10 est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF), Immunocytochemistry (ICC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Détail du produit anti-BCL10 anticorps

Épitope: AA 5-19, N-Term

Specificité: Reacts with human Bcl-10.

Purification: Purified

Immunogène: Synthetic peptide corresponding to aa 5-19 (N-terminus ) of human Bcl-10

Isotype: IgG

Information d'application

Indications d'application: Working dilution: Optimal dilution should be determined by the end user.
The following are guidelines only:
IHC-P (10 μg/mL) WB(1 μg/mL) ICC(1 μg/mL)

Restrictions: For Research Use only

Stockage

Buffer: PBS, pH 7.4

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Dilute in PBS or medium that is identical to that used in the assay system.

Stock: -20 °C

Stockage commentaire: Stable for at least one year at -20°C. Avoid multiple freeze-thaw cycles.

Date de péremption: 12 months

Détails sur BCL10

Antigène: BCL10 (B-Cell CLL/lymphoma 10 (BCL10))

Autre désignation: Bcl-10

Sujet: Overexpression of Bcl10 induces JNK, p38, and NF- B activation. Bcl10 interacts with caspase- 9, enhances pro-caspase-9 processing, and induces apoptosis through caspase-9 activation. Bcl10 exhibits a variety of mutations in MALT lymphoma and in B and T cell lymphomas indicating that it may be commonly involved in the pathogenesis of human tumors. Bcl10 is expressed in many human and murine tissues and cell lines.

B-cell lymphoma/leukemia 10 B-cell CLL/lymphoma 10, Bcl-10 CARD-containing molecule enhancing NF-kappa-B CARD-like apoptotic protein, hCLAP CED-3/ICH-1 prodomain homologous E10-like regulator, CIPER Cellular homolog of vCARMEN, cCARMEN Cellular-E10, c-E10 Mammalian CARD-containing adapter molecule E10, mE10 Gene name: BCL10, CARMEN, CIPER, CLAP, IMD37

ID gène: 8915

UniProt: O95999

Pathways: TCR Signaling, Fc-epsilon Receptor Signaling Pathway, Activation of Innate immune Response, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Tube Formation, Positive Regulation of Endopeptidase Activity, BCR Signaling, Ubiquitin Proteasome Pathway, S100 Proteins