TIMP1 anticorps

N° du produit ABIN1819552

Détail du produit anti-TIMP1 anticorps

Antigène: TIMP1 (TIMP Metallopeptidase Inhibitor 1 (TIMP1))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TIMP1 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Functional Studies (Func)

Specificité: Recognizes human TIMP-1 (Tissue Inhibitor of Metalloproteinase -1), a secreted glycoprotein and member of the protease inhibitor I35 (TIMP) family, which is expressed by a wide range of cells, including microvascular endothelial cells, smooth muscle cells, mesangial cells, and some fibroblasts. TIMP-1 acts as a natural extracellular inhibitor of MMPs (matrix metalloproteinases), a group of peptidases involved in degradation of the extracellular matrix, and is also involved in erythropoiesis, through the simulation of the proliferation/differentiation of erythroid progenitors. Studies have shown that a correlation between localized concentrations of TIMP-1 and TIMP-3, may determine cell fate, and that increased expression of TIMP-1, may act as an inhibitor/suppressor of invasive cell growth.

Purification: Affinity purified

Immunogène: Recombinant human TIMP-1.

Type of Immunogen: Recombinant protein

Isotype: IgG

Information d'application

Indications d'application: Approved: ELISA (0.5 - 2 μg/mL), Func, IHC, IHC-P, WB (0.1 - 0.2 μg/mL)

Commentaires:

Target Species of Antibody: Human

Restrictions: For Research Use only

Stockage

Format: Liquid

Reconstitution: Distilled water

Concentration: Lot specific

Buffer: PBS

Conseil sur la manipulation: Aliquot to avoid repeated freezing and thawing.

Stock: 4 °C,-20 °C

Stockage commentaire: Prior to reconstitution, 4°C. Following reconstitution store at -20°C. Avoid freeze-thaw cycles.

Détails sur TIMP1

Antigène: TIMP1 (TIMP Metallopeptidase Inhibitor 1 (TIMP1))

Autre désignation: TIMP1 (TIMP1 Produits)

Synonymes: anticorps TIMP-1, anticorps TIMP1, anticorps DKFZp468A0912, anticorps CLGI, anticorps EPA, anticorps EPO, anticorps HCI, anticorps TIMP, anticorps Timp, anticorps Clgi, anticorps TIMP metallopeptidase inhibitor 1, anticorps tissue inhibitor of metalloproteinase 1, anticorps TIMP1, anticorps Timp1

Sujet: Name/Gene ID: TIMP1

Synonyms: TIMP1, CLGI, EPA, HCI, Metalloproteinase inhibitor 1, TIMP-1, Collagenase inhibitor

ID gène: 7076