HRAS anticorps

N° du produit ABIN1819947

Cet anticorps anti-HRAS est un anticorps Souris Monoclonal détectant HRAS dans WB et ELISA. Adapté pour Humain, Souris, Rat, Chien, Singe, Poulet, Hamster, Porc, Boeuf (Vache), Poisson, Cobaye, Cheval, Xenopus laevis et Poisson zèbre (Danio rerio).

Aperçu rapide pour HRAS anticorps (ABIN1819947)

Antigène: HRAS (HRas proto-oncogene, GTPase (HRAS))

Reactivité: Humain, Souris, Rat, Chien, Singe, Poulet, Hamster, Porc, Boeuf (Vache), Poisson, Cobaye, Cheval, Xenopus laevis, Poisson zèbre (Danio rerio)

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp HRAS est non-conjugé

Application: Western Blotting (WB), ELISA

Clone: H-Ras-03

Détail du produit anti-HRAS anticorps

Specificité: Recognizes human H-Ras, otherwise known as p21Ras, a ubiquitously expressed lipid-anchored GTPase and member of the Ras superfamily of small GTPases, which acts as a molecular signal transduction on/off switch on the inner surface of the plasma membrane and endomembranes. H-Ras, N-Ras and K-Ras4A/4B are highly related RAS genes which regulate pathways involved in cell differentiation, proliferation, adhesion, migration and apoptosis and are known proto-oncogenes. Mutations in the H-Ras gene are responsible for the rare condition known as Costello syndrome characterized by facial, cardiovascular and musculoskeletal abnormalities and mental retardation.

Purification: Protein A purified

Immunogène: Synthetic peptide corresponding to amino acids DIHQYREQIKRVKDSDDC of human H-Ras. Percent identity by BLAST analysis: Human, Chimpanzee, Gorilla, Orangutan, Monkey, Galago, Marmoset, Mouse, Rat, Shrew, Hamster, Panda, Bovine, Dog, Cat, Horse, Pig, Opossum, Guinea pig, Zebra finch, Chicken, Lizard, Xenopus, Catfish, Salmon, Stickleback, Medaka, Pufferfish, Zebrafish (100%), Turkey, Trout (88%).

Type of Immunogen: Synthetic peptide

Isotype: IgG1

Information d'application

Indications d'application: Approved: ELISA, WB (0.5 - 1 μg/mL)

Commentaires:

Target Species of Antibody: Human

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: PBS, 0.09 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: 4°C or -20°C, Avoid freeze-thaw cycles.

Détails sur HRAS

Antigène: HRAS (HRas proto-oncogene, GTPase (HRAS))

Autre désignation: HRAS / H-Ras

Sujet: Name/Gene ID: HRAS
Subfamily: RAS oncogene
Family: Ras GTPase superfamily IPR001806

Synonyms: HRAS, C-H-RAS, C-has/bas p21 protein, C-ras-Ki-2 activated oncogene, C-HA-RAS1, CTLO, H-ras, H-RASIDX, GTP- and GDP-binding peptide B, GTPase HRas, H-Ras-1, HAMSV, HRAS1, K-RAS, Ha-Ras, Ha-Ras1 proto-oncoprotein, Transforming protein p21, N-ras, p21ras, RASH1, C-BAS/HAS, C-ha-ras, p19 H-RasIDX protein

ID gène: 3265

Pathways: Signalisation p53, Signalisation MAPK, Signalisation RTK, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Hepatitis C, Autophagy, Signaling Events mediated by VEGFR1 and VEGFR2, Signaling of Hepatocyte Growth Factor Receptor, Regulation of long-term Neuronal Synaptic Plasticity, VEGF Signaling, BCR Signaling