Rhodopsin anticorps

N° du produit ABIN1820097

Détail du produit anti-Rhodopsin anticorps

Antigène: Rhodopsin (RHO)

Reactivité: Veuillez nous consulter SVP

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp Rhodopsin est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Specificité: Recognizes rhodopsin, a pigment of the retina responsible for the formation of photoreceptor cells and the first events in the perception of light. Rhodopsin consists of the protein opsin and a reversibly bound cofactor, retinal, a photoreactive chromophore. Upon light absorption the 11-cis-retinal is isomerized to all-trans retinal, leading to a change in the shape of rhodopsin. The change activates the associated G protein and triggers a second messenger cascade, eventually resulting in the transmission of a nerve impulse to the brain. The trans-retinal is released and converted back into 11-cis-retinal for re-entry into the cycle. Defects in the gene cause various retinopathies such as retinitis pigmentosa and X-linked congenital stationary night blindness.

Purification: Protein G purified

Immunogène: Bovine rhodopsin.

Type of Immunogen: Purified protein

Clone: 1D4

Isotype: IgG1

Information d'application

Indications d'application: Approved: IHC, IHC-P (1:100), WB (1:1000)

Commentaires:

Target Species of Antibody: Bovine

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: 10 mM HEPES,  pH 7.5, 150 mM sodium chloride, 0.09 % sodium azide, 0.01 % BSA, 50 % glycerol

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: 4°C or -20°C, Avoid freeze-thaw cycles.

Détails sur Rhodopsin

Antigène: Rhodopsin (RHO)

Autre désignation: Rhodopsin / rho (RHO Produits)

Synonymes: anticorps CSNBAD1, anticorps OPN2, anticorps RP4, anticorps RH1, anticorps Rh, anticorps fi06d11, anticorps wu:fi06d11, anticorps zfo2, anticorps zfrho, anticorps Noerg1, anticorps Opn2, anticorps Ops, anticorps opn2, anticorps rh1, anticorps rp4, anticorps xrho, anticorps PIGRHO1, anticorps ops, anticorps RDP1, anticorps RHO, anticorps rhodopsin, anticorps rhodopsin L homeolog, anticorps RHO, anticorps Rho, anticorps rho, anticorps rho.L

Classe de substances: Chemical

Sujet: Name/Gene ID: RHO
Subfamily: Opsin
Family: GPCR

Synonyms: RHO, CSNBAD1, OPN2, Rhodopsin, RP4, Opsin 2, rod pigment, Opsin-2

ID gène: 6010

Pathways: Signalisation WNT, Sensory Perception of Sound, Regulation of G-Protein Coupled Receptor Protein Signaling, Phototransduction