Lipoprotein Lipase anticorps (AA 380-410)

N° du produit ABIN1820143

Détail du produit anti-Lipoprotein Lipase anticorps

Antigène: Lipoprotein Lipase (LPL)

Épitope: AA 380-410

Reactivité: Humain, Rat, Boeuf (Vache), Porc, Cobaye, Poulet

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp Lipoprotein Lipase est non-conjugé

Application: Western Blotting (WB), ELISA, Immunoprecipitation (IP), Functional Studies (Func)

Specificité: Recognizes an epitope within amino acids 380-410 of lipoprotein lipase (LPL), a member of the AB hydrolase superfamily, which plays a pivotal role in lipoprotein metabolism and transport, acting as the key enzyme in the hydrolysis of triglycerides and very low density lipoproteins (VLDLs), and the release of free fatty acids into peripheral tissues. A deficiency of LPL can result in hypertriglyceridemia, and many studies have focused on the critical role which LPL plays in the pathogenesis of atherosclerosis, and in particular the relationship between LPL and apolipoprotein E (ApoE), both of which are secreted in significant amounts by macrophages in developing arterial wall lesions. Clone 5D2 is a unique antibody which differentiates between monomeric inactive and dimeric active LPL, and binds to LPL sequences involved in LPL, LPL receptor, and heparin interactions. Clone 5D2 has been shown to inhibit the activity of human LPL(2,3), and is widely used in human studies.

Aucune reactivité croisée: Souris

Purification: Protein G purified

niveau d'endotoxine: Low Endotoxin

Immunogène: Purified bovine milk lipoprotein lipase.

Type of Immunogen: Purified protein

Clone: 5D2

Isotype: IgG1

Information d'application

Indications d'application: Approved: ELISA (1:500 - 1:5000), Func, IP, WB

Usage: The applications listed have been tested for the unmodified form of this product. Other forms have not been tested.

Commentaires:

Target Species of Antibody: Bovine

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: PBS

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze-thaw cycles.

Détails sur Lipoprotein Lipase

Antigène: Lipoprotein Lipase (LPL)

Autre désignation: Lipoprotein Lipase / LPL (LPL Produits)

Synonymes: anticorps HDLCQ11, anticorps LIPD, anticorps fb62e04, anticorps fc49b03, anticorps wu:fb62e04, anticorps wu:fc49b03, anticorps LPL, anticorps lipd, anticorps hdlcq11, anticorps lpl, anticorps LOC100223817, anticorps lipoprotein lipase, anticorps LPL, anticorps Lpl, anticorps lpl

Sujet: Name/Gene ID: LPL

Synonyms: LPL, LIPD, Lipoprotein lipase, HDLCQ11

ID gène: 4023

Pathways: Lipid Metabolism