C-JUN anticorps (AA 41-70)

N° du produit ABIN1881470

L’anticorps Lapin Polyclonal anti-C-JUN a été validé pour WB. Il convient pour détecter C-JUN dans des échantillons de Humain. Il y a 3+ publications disponibles.

Aperçu rapide pour C-JUN anticorps (AA 41-70) (ABIN1881470)

Antigène: C-JUN (JUN) (Jun Proto-Oncogene (JUN))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp C-JUN est non-conjugé

Application: Western Blotting (WB)

Clone: RB11002

Détail du produit anti-C-JUN anticorps

Épitope: AA 41-70

Homologie: B, M, Rat

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogène: This JUN antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 41-70 amino acids from human JUN.

Isotype: Ig Fraction

Information d'application

Indications d'application: WB: 1:1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Date de péremption: 6 months

Références pour anticorps anti-C-JUN (ABIN1881470)

Madhunapantula, Robertson: "Is B-Raf a good therapeutic target for melanoma and other malignancies?" dans: Cancer research, Vol. 68, Issue 1, pp. 5-8, (2008) (PubMed).

Fujita, Ito, Mizutani, Minoguchi, Yamamichi, Sakurai, Iba: "miR-21 Gene expression triggered by AP-1 is sustained through a double-negative feedback mechanism." dans: Journal of molecular biology, Vol. 378, Issue 3, pp. 492-504, (2008) (PubMed).

Gan, Wang, Xi, Wu, Li, Li: "Nuclear Dvl, c-Jun, beta-catenin, and TCF form a complex leading to stabilization of beta-catenin-TCF interaction." dans: The Journal of cell biology, Vol. 180, Issue 6, pp. 1087-100, (2008) (PubMed).

Détails sur C-JUN

Antigène: C-JUN (JUN) (Jun Proto-Oncogene (JUN))

Autre désignation: JUN

Sujet: JUN interacts directly with specific target DNA sequences to regulate gene expression. Jun recognizes the AP-1 consensus sequence TGACTCA, a response element that confers sensitivity to one of the tumor-promoting Phorbol esters, 12-O-tetradecanoyl-phorbol-13-acetate (see also: TRE, TPA response element). Jun itself forms homodimers or heterodimers with junD and junB and also interacts with the oncogene product fos, forming jun-fos heterodimers.

Poids moléculaire: 35676

NCBI Accession: NP_002219

UniProt: P05412

Pathways: Signalisation MAPK, Signalisation RTK, Signalisation WNT, Fc-epsilon Receptor Signaling Pathway, Activation of Innate immune Response, Myometrial Relaxation and Contraction, Skeletal Muscle Fiber Development, Protein targeting to Nucleus, Toll-Like Receptors Cascades, Autophagy, Signaling of Hepatocyte Growth Factor Receptor, BCR Signaling, S100 Proteins