ERK1 anticorps (AA 182-211)

N° du produit ABIN1881527

Il existe 6+ publications pour ce produit. L’anticorps anti-ERK1 Polyclonal Lapin est utilisé pour la détection de ERK1 dans des échantillons de Humain. Il a été validé pour WB.

Aperçu rapide pour ERK1 anticorps (AA 182-211) (ABIN1881527)

Antigène: ERK1 (MAPK3) (Mitogen-Activated Protein Kinase 3 (MAPK3))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ERK1 est non-conjugé

Application: Western Blotting (WB)

Clone: RB13301

Détail du produit anti-ERK1 anticorps

Épitope: AA 182-211

Homologie: D, B, M, Rat, X, E

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogène: This MAPK3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 182-211 amino acids from human MAPK3.

Isotype: Ig Fraction

Information d'application

Indications d'application: WB: 1:1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Date de péremption: 6 months

Références pour anticorps anti-ERK1 (ABIN1881527)

Tetsunaga, Nishida, Furumatsu, Naruse, Hirohata, Yoshida, Saito, Ozaki: "Regulation of mechanical stress-induced MMP-13 and ADAMTS-5 expression by RUNX-2 transcriptional factor in SW1353 chondrocyte-like cells." dans: Osteoarthritis and cartilage / OARS, Osteoarthritis Research Society, Vol. 19, Issue 2, pp. 222-32, (2011) (PubMed).

Munshi, Wu, Mukhopadhyay, Ottaviano, Sassano, Koblinski, Platanias, Stack et al.: "Differential regulation of membrane type 1-matrix metalloproteinase activity by ERK 1/2- and p38 MAPK-modulated tissue inhibitor of metalloproteinases 2 expression controls transforming growth ..." dans: The Journal of biological chemistry, Vol. 279, Issue 37, pp. 39042-50, (2004) (PubMed).

Mukherjee, Huang, Petkova, Albanese, Pestell, Braunstein, Christ, Wittner, Lisanti, Berman, Weiss, Tanowitz: "Trypanosoma cruzi infection activates extracellular signal-regulated kinase in cultured endothelial and smooth muscle cells." dans: Infection and immunity, Vol. 72, Issue 9, pp. 5274-82, (2004) (PubMed).

Sebkova, Pellicanò, Monteleone, Grazioli, Guarnieri, Imeneo, Pallone, Luzza: "Extracellular signal-regulated protein kinase mediates interleukin 17 (IL-17)-induced IL-8 secretion in Helicobacter pylori-infected human gastric epithelial cells." dans: Infection and immunity, Vol. 72, Issue 9, pp. 5019-26, (2004) (PubMed).

Huang, Chang, Liu: "Basic fibroblast growth factor antagonizes activin A-mediated growth inhibition and hemoglobin synthesis in K562 cells by activating ERK1/2 and deactivating p38 MAP kinase." dans: Biochemical and biophysical research communications, Vol. 320, Issue 4, pp. 1247-52, (2004) (PubMed).

Mizuno, Kadowaki, Demura, Ameshima, Miyamori, Ishizaki: "p42/44 Mitogen-activated protein kinase regulated by p53 and nitric oxide in human pulmonary arterial smooth muscle cells." dans: American journal of respiratory cell and molecular biology, Vol. 31, Issue 2, pp. 184-92, (2004) (PubMed).

Détails sur ERK1

Antigène: ERK1 (MAPK3) (Mitogen-Activated Protein Kinase 3 (MAPK3))

Autre désignation: MAPK3

Sujet: MAPK3 is a member of the MAP kinase family. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act in a signaling cascade that regulates various cellular processes such as proliferation, differentiation, and cell cycle progression in response to a variety of extracellular signals. This kinase is activated by upstream kinases, resulting in its translocation to the nucleus where it phosphorylates nuclear targets.

Poids moléculaire: 43136

NCBI Accession: NP_001035145, NP_001103361, NP_002737

UniProt: P27361

Pathways: Signalisation MAPK, Signalisation RTK, Interferon-gamma Pathway, Fc-epsilon Receptor Signaling Pathway, Neurotrophin Signaling Pathway, Response to Growth Hormone Stimulus, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Hepatitis C, Protein targeting to Nucleus, Toll-Like Receptors Cascades, Signaling Events mediated by VEGFR1 and VEGFR2, Signaling of Hepatocyte Growth Factor Receptor, VEGFR1 Specific Signals, S100 Proteins