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PSMC1 anticorps (C-Term)

PSMC1 Reactivité: Humain, Souris, Rat WB, IHC (p), IF Hôte: Lapin Polyclonal RB44417 unconjugated
N° du produit ABIN1881692
  • Antigène Voir toutes PSMC1 Anticorps
    PSMC1 (Proteasome (Prosome, Macropain) 26S Subunit, ATPase, 1 (PSMC1))
    Épitope
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 408-436, C-Term
    Reactivité
    • 22
    • 18
    • 16
    • 5
    • 5
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Humain, Souris, Rat
    Hôte
    • 22
    Lapin
    Clonalité
    • 22
    Polyclonal
    Conjugué
    • 15
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp PSMC1 est non-conjugé
    Application
    • 15
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)
    Purification
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    Immunogène
    This PRS4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 408-436 amino acids from the C-terminal region of human PRS4.
    Clone
    RB44417
    Isotype
    Ig Fraction
  • Indications d'application
    IF: 1:25. WB: 1:1000. IHC-P: 1:25
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    4 °C,-20 °C
    Date de péremption
    6 months
  • Katiyar, Li, Lennarz: "A complex between peptide:N-glycanase and two proteasome-linked proteins suggests a mechanism for the degradation of misfolded glycoproteins." dans: Proceedings of the National Academy of Sciences of the United States of America, Vol. 101, Issue 38, pp. 13774-9, (2004) (PubMed).

    Matilla, Gorbea, Einum, Townsend, Michalik, van Broeckhoven, Jensen, Murphy, Ptácek, Fu: "Association of ataxin-7 with the proteasome subunit S4 of the 19S regulatory complex." dans: Human molecular genetics, Vol. 10, Issue 24, pp. 2821-31, (2001) (PubMed).

    Dubiel, Ferrell, Pratt, Rechsteiner: "Subunit 4 of the 26 S protease is a member of a novel eukaryotic ATPase family." dans: The Journal of biological chemistry, Vol. 267, Issue 32, pp. 22699-702, (1992) (PubMed).

  • Antigène
    PSMC1 (Proteasome (Prosome, Macropain) 26S Subunit, ATPase, 1 (PSMC1))
    Abstract
    PSMC1 Produits
    Synonymes
    anticorps AI325227, anticorps P26s4, anticorps S4, anticorps P26S4, anticorps p56, anticorps s4, anticorps protease (prosome, macropain) 26S subunit, ATPase 1, anticorps proteasome 26S subunit, ATPase 1, anticorps Psmc1, anticorps PSMC1
    Sujet
    The 26S protease is involved in the ATP-dependent degradation of ubiquitinated proteins. The regulatory (or ATPase) complex confers ATP dependency and substrate specificity to the 26S complex.
    Poids moléculaire
    49185
    NCBI Accession
    NP_002793
    UniProt
    P62191
    Pathways
    Mitotic G1-G1/S Phases, DNA Replication, Synthesis of DNA, Ubiquitin Proteasome Pathway
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