LY96 anticorps (AA 2-160)

N° du produit ABIN1885505

Détail du produit anti-LY96 anticorps

Antigène: LY96 (Lymphocyte Antigen 96 (LY96))

Épitope: AA 2-160

Reactivité: Humain, Souris, Rat

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp LY96 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Purification: Immunoaffinity chromotography purified IgG

Immunogène: Raised against a recombinant protein corresponding to amino acids 2 to 160 of human MD-2

Information d'application

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS containing 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.

Stock: -20 °C

Stockage commentaire: Can be stored at -20 °C, stable for one year.

Date de péremption: 12 months

Détails sur LY96

Antigène: LY96 (Lymphocyte Antigen 96 (LY96))

Autre désignation: MD-2 (LY96 Produits)

Synonymes: anticorps MD2, anticorps ESOP-1, anticorps MD-2, anticorps ly-96, anticorps Ly-96, anticorps Md2, anticorps lymphocyte antigen 96, anticorps LY96, anticorps Ly96

Sujet: MD-2 is a member of the Toll/interleukin-1 receptor (TIR) family, a group of proteins that include the Toll-like receptors (TLRs).TLRs are signaling molecules that recognize different pathogen-associated molecular patterns (PAMPs) and serve as an important link between the innate and adaptive immune responses.TLR4, the major signaling receptor for lipopolysaccharide (LPS), requires the binding of MD-2 to its extracellular region for maximal response to LPS.Theof this response is determined by the species of MD-2, e.g., human MD-2 transfected into mouse cells can cause mouse TLR4 to react to LPS analogs that are normally antagonistic to human but not mouse TLR4.
Synonyms: MD-2 (1A2E3).Lymphocyte antigen 96 precursor, ESOP-1

NCBI Accession: NP_056179

Pathways: Signalisation TLR, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Toll-Like Receptors Cascades