BIM anticorps (AA 2-198)

N° du produit ABIN1885509

Détail du produit anti-BIM anticorps

Antigène: BIM (BCL2L11) (BCL2-Like 11 (Apoptosis Facilitator) (BCL2L11))

Épitope: AA 2-198

Reactivité: Humain, Souris

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp BIM est non-conjugé

Application: Western Blotting (WB), ELISA, Immunocytochemistry (ICC)

Purification: Immunoaffinity chromotography purified IgG

Immunogène: Raised against a recombinant protein corresponding to amino acids 2 to 198 of human Bim.

Information d'application

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS containing 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.

Stock: -20 °C

Stockage commentaire: Can be stored at -20 °C, stable for one year.

Date de péremption: 12 months

Détails sur BIM

Antigène: BIM (BCL2L11) (BCL2-Like 11 (Apoptosis Facilitator) (BCL2L11))

Autre désignation: Bim (BCL2L11 Produits)

Synonymes: anticorps bim, anticorps BAM, anticorps BIM, anticorps BOD, anticorps 1500006F24Rik, anticorps Bim, anticorps Bod, anticorps BimL, anticorps BIMEL, anticorps BCL2-like 11, anticorps BCL2 like 11, anticorps BCL2-like 11 (apoptosis facilitator), anticorps bcl2l11, anticorps BCL2L11, anticorps Bcl2l11

Sujet: Members in the Bcl-2 family are critical regulators of apoptosis by either inhibiting or promoting cell death.Bcl-2 homology 3 (BH3) domain is a potent death domain.BH3 domain containing pro-apoptotic proteins, including Bad, Bax, Bid, Bik, and Hrk, form a growing subclass of the Bcl-2 family.Bim is another BH3 domain containing protein which can induce apoptosis.Bim interacts with diverse members in the pro-survival Bcl-2 sub-family including Bcl-2, Bcl-xL and Bcl-w.The messenger RNA of Bim is ubiquitously expressed in multiple tissues and cell lines.
Synonyms: Bim (1C2C8).Bcl-2 interacting protein, Bcl-2-related ovarian death gene, BOD, Bcl-2-like 11

NCBI Accession: NP_619527

Pathways: Signalisation PI3K-Akt, Neurotrophin Signaling Pathway, Tube Formation, Positive Regulation of Endopeptidase Activity