HRAS anticorps (AA 111-176)

N° du produit ABIN1885963

Cet anticorps Lapin Polyclonal détecte spécifiquement HRAS dans WB, IHC et IF. Il présente une réactivité envers Humain.

Aperçu rapide pour HRAS anticorps (AA 111-176) (ABIN1885963)

Antigène: HRAS (HRas proto-oncogene, GTPase (HRAS))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp HRAS est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Détail du produit anti-HRAS anticorps

Épitope: AA 111-176

Purification: Purified by antigen-affinity chromatography.

Immunogène: Synthetic peptide contain a sequence corresponding to a region within amino acids 111 and 176 of H-Ras

Information d'application

Indications d'application: Suggested dilutions:
Western blotting: 1.500-1.3000
Immunohistochemistry: 1.100-1.500
Immunofluorescence: 1.100-1.200

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: 0.1 M Tris-buffered saline with 20 % Glycerol (pH 7.0).0.01 % Thimerosal was added as a preservative.

Agent conservateur: Thimerosal (Merthiolate)

Précaution d'utilisation: Biohazard Informations: This product contains thimerosal which is hazardous.

Stock: 4 °C/-20 °C

Stockage commentaire: Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.

Détails sur HRAS

Antigène: HRAS (HRas proto-oncogene, GTPase (HRAS))

Autre désignation: H-Ras

Sujet: This gene belongs to the Ras oncogene family, whose members are related to the transforming genes of mammalian sarcoma retroviruses.The products encoded by these genes function in signal transduction pathways.These proteins can bind GTP and GDP, and they have intrinsic GTPase activity.This protein undergoes a continuous cycle of de- and re-palmitoylation, which regulates its rapid exchange between the plasma membrane and the Golgi apparatus.Mutations in this gene cause Costello syndrome, a disease characterized by increased growth at the prenatal stage, growth deficiency at the postnatal stage, predisposition to tumor formation, mental retardation, skin and musculoskeletal abnormalities, distinctive facial appearance and cardiovascular abnormalities.Defects in this gene are implicated in a variety of cancers, including bladder cancer, follicular thyroid cancer, and oral squamous cell carcinoma.Multiple transcript variants, which encode different isoforms, have been identified for this gene.[provided by RefSeq]

Poids moléculaire: 21 kDa

ID gène: 3265

NCBI Accession: NM_005343, NP_005334

Pathways: Signalisation p53, Signalisation MAPK, Signalisation RTK, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Hepatitis C, Autophagy, Signaling Events mediated by VEGFR1 and VEGFR2, Signaling of Hepatocyte Growth Factor Receptor, Regulation of long-term Neuronal Synaptic Plasticity, VEGF Signaling, BCR Signaling