ELF3 anticorps (AA 309-371)

N° du produit ABIN1886354

Détail du produit anti-ELF3 anticorps

Antigène: ELF3 (E74-Like Factor 3 (Ets Domain Transcription Factor, Epithelial-Specific) (ELF3))

Épitope: AA 309-371

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ELF3 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Purification: Purified by antigen-affinity chromatography.

Immunogène: Synthetic peptide contain a sequence corresponding to a region within amino acids 309 and 371 of ESE1

Information d'application

Indications d'application: Suggested dilutions:
Western blotting: 1.500-1.3000
Immunohistochemistry: 1.100-1.250
Immunofluorescence: 1.100-1.200

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: 1 x PBS, 1 % BSA, 20 % Glycerol (pH 7.0).0.01 % Thimerosal was added as a preservative.

Agent conservateur: Thimerosal (Merthiolate)

Précaution d'utilisation: Biohazard Informations: This product contains thimerosal which is hazardous.

Stock: 4 °C/-20 °C

Stockage commentaire: Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.

Détails sur ELF3

Antigène: ELF3 (E74-Like Factor 3 (Ets Domain Transcription Factor, Epithelial-Specific) (ELF3))

Autre désignation: ESE1 (ELF3 Produits)

Synonymes: anticorps ert, anticorps esx, anticorps epr-1, anticorps ese-1, anticorps ESE-1, anticorps ESX, anticorps jen, anticorps EPR-1, anticorps ERT, anticorps E74 like ETS transcription factor 3, anticorps E74-like factor 3, anticorps elf3, anticorps Elf3, anticorps ELF3

Sujet: Transcriptional activator that binds and transactivates ETS sequences containing the consensus nucleotide core sequence GGA[AT].Acts synergistically with POU2F3 to transactivate the SPRR2A promoter and with RUNX1 to transactivate the ANGPT1 promoter.Also transactivates collagenase, CCL20, CLND7, FLG, KRT8, NOS2, PTGS2, SPRR2B, TGFBR2 and TGM3 promoters.Represses KRT4 promoter activity.Involved in mediating vascular inflammation.May play an important role in epithelial cell differentiation and tumorigenesis.May be a critical downstream effector of the ERBB2 signaling pathway.May be associated with mammary gland development and involution.Plays an important role in the regulation of transcription with TATA-less promoters in preimplantation embryos, which is essential in preimplantation development.

Poids moléculaire: 41 kDa

ID gène: 1999

NCBI Accession: NM_004433, NP_004424