Activin A Receptor Type IB/ALK-4 anticorps (C-Term)

N° du produit ABIN1886993

Détail du produit anti-Activin A Receptor Type IB/ALK-4 anticorps

Antigène: Activin A Receptor Type IB/ALK-4 (ACVR1B) (Activin A Receptor, Type IB (ACVR1B))

Épitope: C-Term

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Activin A Receptor Type IB/ALK-4 est non-conjugé

Application: Western Blotting (WB), ELISA

Réactivité croisée (Details): At least three isoforms of ACVR1B are known to exist. This antibody is predicted to have no cross-reactivity to ACVR1 or ACVR1C.

Purification: Affinity chromatography purified via peptide column

Immunogène: 14 amino acid peptide near the carboxy terminus of the human ACVR1B.

Information d'application

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS containing 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.

Conseil sur la manipulation: Avoid freezing and thawing repeatly.

Stock: 4 °C/-20 °C

Stockage commentaire: Store at 4 °C for short term use.Store at -20 °C for long term preservation.

Détails sur Activin A Receptor Type IB/ALK-4

Antigène: Activin A Receptor Type IB/ALK-4 (ACVR1B) (Activin A Receptor, Type IB (ACVR1B))

Autre désignation: ACVR1B (ACVR1B Produits)

Synonymes: anticorps ACVR1B, anticorps alk4, anticorps skr2, anticorps alk-4, anticorps xalk4, anticorps actrib, anticorps acvrlk4, anticorps DKFZp469A1614, anticorps 6820432J04, anticorps ActR-IB, anticorps ActRIB, anticorps Acvrlk4, anticorps Alk4, anticorps SKR2, anticorps ACTRIB, anticorps ACVRLK4, anticorps ALK4, anticorps Skr2, anticorps axis, anticorps taram-a, anticorps tarama, anticorps wu:fb75f01, anticorps activin A receptor type 1B, anticorps Activin receptor type-1B, anticorps activin A receptor, type IB, anticorps activin A receptor, type 1B, anticorps activin A receptor type 1Ba, anticorps ACVR1B, anticorps acvr1b, anticorps acv1b, anticorps Acvr1b, anticorps acvr1ba

Sujet: Activins are dimeric growth and differentiation factors which belong to the transforming growth factor-beta (TGF-beta) superfamily of structurally related signaling proteins.Activins signal through a heteromeric complex of receptor serine kinases which include at least two type I and two type II receptors.ACVR1B, also known as activin receptor-like kinase 4 (ALK4), is a type I receptor for activin and plays major roles in cell differentiation, growth arrest and apoptosis.Like another type I activin receptor ACVR1C, ACVR1B can mediate signaling by ligands such as Nodal, Xnr1, GDF-1/3, activin B and activin AB.In Xenopus embryos, expression of a dominant-negative form of ACVR1B blocked all mesoderm-inducing ligands, while expression of a dominant negative ACVR1C only blocked Nodal and Xnr1 signaling, suggesting that the ACVR1B and ACVR1C possess distinct functions.
Synonyms: Activin A receptor type IB, Activin receptor-like kinase 4, Activin receptor type 1B precursor, ACTR-IB, ACVRLK4, ALK4, ALK-4

NCBI Accession: NP_001096