2B4 anticorps (C-Term)

N° du produit ABIN1887149

Détail du produit anti-2B4 anticorps

Antigène: 2B4 (CD244) (Natural Killer Cell Receptor 2B4 (CD244))

Épitope: C-Term

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp 2B4 est non-conjugé

Application: Western Blotting (WB), ELISA

Réactivité croisée (Details): At least three isoforms of SLAMF4 are known to exist. SLAMF4 antibody is predicted to not cross-react with other SLAM protein family members.

Purification: Affinity chromatography purified via peptide column

Immunogène: 16 amino acid peptide near the carboxy terminus of human SLAMF4.

Information d'application

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS containing 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.

Conseil sur la manipulation: Avoid freezing and thawing repeatly.

Stock: 4 °C/-20 °C

Stockage commentaire: Store at 4 °C for short term use.Store at -20 °C for long term preservation.

Détails sur 2B4

Antigène: 2B4 (CD244) (Natural Killer Cell Receptor 2B4 (CD244))

Autre désignation: SLAMF4 (CD244 Produits)

Synonymes: anticorps CD244, anticorps 2B4, anticorps NAIL, anticorps NKR2B4, anticorps Nmrk, anticorps SLAMF4, anticorps C9.1, anticorps F730046O15Rik, anticorps Ly90, anticorps CD244 molecule, anticorps CD244 natural killer cell receptor 2B4, anticorps CD244, anticorps Cd244

Sujet: The signaling lymphocyte-activation molecule family member 4 (SLAMF4), also known as 2B4, is an important regulator of Natural Killer (NK) cell activation.It is expressed on NK cells as well as on subsets of T cells and interacts with SLAMF2, causing the activation of both SLAMF4- and SLAMF2-expressing cells.Patients with systemic lupus erythmatosus have lower than normal levels of SLAMF4 expressed on their NK cells and monocytes, suggesting that SLAMF4 may play a role in this autoimmune disease.
Synonyms: Signaling lymphocytic activation molecule family member 4, natural killer cell receptor 2B4, NKR2B4, 2B4, NAIL, NMRK, CD244

NCBI Accession: NP_1160135